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Utero

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Utero is the alternate floor of The Womb, and looks exactly the same. The only difference is the variety of enemies and bosses that appear. This floor was added in the Wrath of the Lamb DLC

Rooms

  • 1: The room will always appear once in this floor
  • 2: The room will always appear twice in this floor
  • Possible: There is a chance for this room to appear, usually due to certain criteria being met
  • -: The room cannot appear in this floor.


Rooms from the core game
Rooms Utero 1 Utero 2 Utero XL Note
Regular Rooms 22 - 26 22 - 26 39 - 40
Treasure room icon Treasure Room - - - From The Womb/Utero and onwards, no more Treasure Rooms will appear.
Shop icon Shop - - - From The Womb/Utero and onwards, no more Shops will appear.
Secret room icon Secret Room 1 1 1
BossRoomIcon Boss Room 1 1 2 Boss Rooms are always linked in XL floors.
Challegne room icon Challenge Room Possible Possible Possible Will only be generated if Isaac has full health while entering the floor.
Arcade icon Arcade - Possible Possible Only generated when Isaac has 5 Coins upon entering a new floor or part.
Super secret room icon Devil Room Possible Possible Possible If the Devil Room is entered at Utero 2/Utero XL, there will be a trapdoor leading to Sheol instead of items being sold for Heart Containers. The trapdoor appears even if the player has not killed It Lives!.
Super secret room icon I AM ERROR Possible Possible Possible Only reachable by using the Telepills, which have a 6.66% chance to teleport Isaac to this room.
Rooms with Wrath of the Lamb
Rooms Utero 1 Utero 2 Utero XL Note
Super secret room icon Super Secret Room 1 1 1
Curse room icon Curse Room Possible Possible Possible
Sacrifice room icon Sacrifice Room Possible Possible Possible
Angel room icon Angel Room Possible Possible Possible If the Angel Room is entered at Utero 2/Utero XL, there will be a trapdoor leading to Sheol instead of an item at a pedestal. The trapdoor appears even if the player has not killed It Lives!.
Libary icon Library Possible Possible Possible 5% base chance to spawn, 25% if Isaac is holding a book.
Boss challenge room Boss Challenge Room Possible Possible Possible

Monsters

Monster Description WotL DLC
Fat Fly
Superpooter
Alternate version of PootersPouter. Fires 2 shots in a V-formation and does not deal touch damage.
Spit
Puffer
Flies slowly towards Isaac, exploding into an IPECAC shot upon death which targets other Spits in the room, or Isaac.
Spider
Black spider
Moves erratically around the room, damaging Isaac by touch.
Big Spider
Big spider
Moves erratically around the room, splitting into two SpidersBlack spider upon death.
Gazing Globin
Globin 2
Quickly walks towards Isaac, dealing one heart of contact damage. Turns into a pile of goo and slides away after taking enough damage, where it can be killed. Will regenerate after a short amount of time if not killed quickly.
Mask + Heart
Mask Heart
Invulnerable mask with a slow-moving Heart. Functions similarly to a Knight. The Heart fires 4 blood shots in a plus pattern when Isaac gets near. Killing the Heart will automatically kill the Mask.
Clotty
Clotty
Moves around the room, firing 4 blood shots in a plus pattern.
Clot
Clot2
Moves around the room, firing 4 tar shots in an X pattern.
Brain
Brain
Crawls around the room, leaving a trail of red Creep that does one heart of damage.
Guts
GutsMonster
Attaches itself to a wall or obstacle, such as a Rock, rolling around the room.
Mama Guts
Big guts
Slowly moves around the room, occassionally hopping and firing 8 large blood shots in all directions. Will split into 2 GutsGutsMonster upon death.
Para-Bite
Parabite
Moves towards Isaac. Can burrow underground and reappear elsewhere.
Fred
Fred
Fires an IPECAC shot at Isaac. Will hop out of the ground and burrow elsewhere, firing 4 blood shots in an X pattern while doing so.
Lump
Lump
Fires 3 fast-moving blood shots at Isaac when he gets in its line of sight. Will burrow underground and reappear elsewhere after firing its shots.
Leech
Leech
Quickly charges towards Isaac when he gets in its line of sight.
Kamikaze Leech
Leech2
Quickly charges towards Isaac when he gets in its line of sight. Explodes with a large blast radius upon death.
Holy Leech
Holy leech
Quickly charges towards Isaac when he gets in its line of sight. Explodes with a large blast radius upon death. Has an Eternal FlyWhite fly circling it.
Double Vis
Vis Fio
Charges up a Brimstone laser which fires from both sides when Isaac gets in its line of sight.
Eye
Eye
Quickly fires a Technology-like laser at Isaac.
Bloodshot Eye
BloodshotEye
Quickly fires a Brimstone-like laser at Isaac.
Dople
Dople1
Copies Isaac's movements, and fires tears at the same time as him.
Evil Twin
Dople 2
Copies Isaac's movements, and fires tears at the same time as him.
Baby
Boby
Fires a single blood shot at Isaac. Can teleport and reappear elsewhere.
Angelic Baby
Angel baby
Fires 3 blood shots at once at Isaac, has much more health than regular Babies.
Vomit Grimace
VomitTurret
Stationary and invulnerable monster that fires an IPECAC shot at Isaac. Stops firing when room is cleared.
Minibosses (7 Sins) found in normal rooms:
Wrath
Wrath
Usually paired with another Wrath. Fires Bombs at Isaac that detonate after a short amount of time, in a manner similar to Dr. Fetus.
Sloth
Sloth
Usually paired with another Sloth. Fires IPECAC shots at Isaac, while occasionally spawning ChargersCharger
Envy
Envy
Usually paired with another Envy. Moves around the room slowly at first, and then splits into two faster-moving heads after taking enough damage. These heads will split into two more heads with a smaller size and increased speed after taking enough damage, which will then split into the smallest heads that do not split.
Bosses found in normal rooms:
Blastocyst
Blastocyst full
Hops around the room, firing 4 large blood shots in a + pattern. Splits into two smaller parts upon taking enough damage, and into an Embyro at the end.
Gemini
Gemini full
Two joined twins that compose 50% of the health bar each. The large twin runs towards Isaac, while the smaller twin fires fast-moving blood shots. The smaller twin will stop firing blood shots upon the larger twin's death, and instead start chasing Isaac.
Fistula
Fistula
Floats around the room diagonally, splitting into smaller, faster versions every time it takes damage. Smallest versions spawn a ChargerCharger when killed.
Gurdy Jr.
Gurdjr
Spawns Pooters regularly, and can fire blood shots in all 8 directions. Will occasionally charge towards Isaac at very high speeds, bouncing off walls.
The Husk
The Husk
Moves around the room diagonally, spawning Flies and firing a large number of blood shots in short intervals.
The Hollow
260x220-The Hollow2
Two multi-segmented enemies that fly around the room diagonally, damaging Isaac by contact. All of the segments have to be destroyed for the boss to be killed.
Loki
Loki full
Constantly fires 4 blood shots in a plus or cross pattern, and sometimes in all 8 directions at once. Occasionally teleports around the room. Can spawn Boom FliesBoomfly

Bosses

Trivia

  • "Uterus" is the Latin word for womb. This spelling indicates that the word is being used in the ablative case, suggesting its use as a location as in the phase in utero, "in the womb."
Chapters
No Core Game Wrath of the Lamb
1 Basement Cellar *
2 Caves Catacombs *
3 The Depths Necropolis *
4 The Womb Utero *
5 Sheol Cathedral
6 The Dark Room The Chest
* Alternate Chapters

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