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  • Thought i'd make a post where we'd post a list of OP seeds, Over powered is when you can beat mom's heart in less than 30 seconds, the format would be like this:

    Seed:

    Best Character for the seed:

    The Items:

    Example

    Seed: 0BBJ ZEN1

    Best Character for the seed: Azazel

    The Items: Polyphemus, Ludovico technique, Spoon bender, The Pact, Prayer Card, Experimental treatment.


    Edit: Oh and about the seed unlocks, endings 14, 15 and 16 will unlock in seeds.

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    • 67G1 T461 Eden. you start with unicorn stump and knive

      later you can bay the 9 volt and use it multiple times per rooms such as satan. along the way you get stompy which makes nothing able to block you, then just to finish it off you get quad shot.

      probably one of my quickest runs, and so much fun

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    • Chuzzymcfuzzy
      Chuzzymcfuzzy removed this reply because:
      I didn't see the format.
      07:06, September 24, 2015
      This reply has been removed
    • Seed: AV7Z4042

      Best Character for the seed: EDEN 

      The Items: Crickets Body, Doctor's remote,  brimstone, spoonbender, goathead, guppy's head, guppy's tail, dead cat and guppy's paw, more options.

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    • Chuzzymcfuzzy wrote:

      Seed: AV7Z4042

      Best Character for the seed: EDEN 

      The Items: Crickets Body, Doctor's remote,  brimstone, spoonbender, goathead, guppy's head, guppy's tail, dead cat and guppy's paw, more options.

      i love you, i became guppy in the first curse room! :D

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    • Chuzzymcfuzzy wrote:

      Seed: AV7Z4042

      Best Character for the seed: EDEN 

      The Items: Crickets Body, Doctor's remote,  brimstone, spoonbender, goathead, guppy's head, guppy's tail, dead cat and guppy's paw, more options.

      This seed gave me my first Lamb kill AND one of the most OP item runs I've seen

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    • I'm sure something like this has happened to someone somewhere at some point, but this is the most stupid OP Isaac happen-about I've had or seen. So ridiculous in the most not flashy way.

      FIRST FLOOR:

      Up - Ipecac (Do You Even Damage?)

      Left - Chest Containing Lucky Rock (Puke on Rocks)

      Shop - 1+1 (Puke on More Rocks)

      Down - Black Market Trap-door w/ Magic Fingers (Scales w/ Damage)

      YUPYUPYUPYUPYuuuup You can now tap your spacebar to all the victory.


      This was originally a Judas run. What makes this pretty much literally the easiest run of anyones lives is that this is all on the first floor. See how fast you can clear the game with unlimited high power magic fingers. The only thing slowing you down is how fast you can replenish pennies.


      I don't advise taking Mom's Knife in the Necropolis Devil Room. As per usual, it can only ever gum up your run. Tested to find out it severely cuts the damage. There are potentially other combos of greatness in this seed.

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    • ^^^^^     RNM4 KKQ7     ^^^^^

      Whoops.

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    • SYYJ

      3108

      Best character: I used Cain, don't know if it was te best character.

      Items: Ohh boy. 1st floor treasure room: Polyphemus. 1st floor boss: Monstro, drops hp up. 2nd floor treasure room: Prayer card. 2nd floor boss: Widow, drops hp up. Devil room: (And here it gets fun): Abbadon (guppy's tail and brother bobby as well, but abbadon is the best one). 3rd foor treasure room: Teleport (nothing too good) 3rd floor boss: Monstro double trouble, drops Box. Pill is paralysis. 4t floor treasure room: LUDOVICO TECHNIQUE. YES. IT'S HERE. Eventually you get Krampus, who drops Lump of coal, making it more overpowered if you're far away. Later on, you get a devil room with Mom's knife.

      I swear to God almighty, I got to It Lives and got it down to 1/2 health before i killed the eyes. Fucking helpless. I love it.

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    • ^ Well, the second boss was Larry JR. with a new mob that I've never seen before. I'm right now actually retrying your seed because I died, but so far so good. Nice seed! :)

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    • Seed - 6T23-49WH

      I did it with cain and its a floor 1 missing no and TAKE EVERYTHING.

      I got I think most to all of the new trasformations.

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    • FEAR M1NT

      Everything is scared of you but random floor every time.

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    • 86.3.21.168 wrote:
      ^ Well, the second boss was Larry JR. with a new mob that I've never seen before. I'm right now actually retrying your seed because I died, but so far so good. Nice seed! :)

      No, its just you didnt unlock cellar, so you didnt get widow. if you unlock cellar, its widow.

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    • I had an OP Seed too

      3 dmg up

      79YS

      D211

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    • I will come on this and comment on it before 30 days so it doesnt die

      got it everyone

      I might post a seed eventually if I ever get one

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    • Smart

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    • AACL 71K7

      isaac i guess... first item ipecac, depths 1: cricket´s head and you become guppy with hivemind

      imagine those flies´ damage uh oh

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    • objy epdx


      use azazel

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    • are any of those seeds good for afterbirth, tested most of them and got different items so im guessing no? If not could someone please give me a good afterbirth seed? Thanks

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    • 88.137.117.225 wrote:
      are any of those seeds good for afterbirth, tested most of them and got different items so im guessing no? If not could someone please give me a good afterbirth seed? Thanks

      SJ61 JCJP

      Here you go ^-^

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    • i had a seed where i got a dime and an item room with a reroll machine use the reroll machine 3 times to get tech x the choas in a shop in caves or necropolis you can get triple shot if you dont get choas and spoon bender if you do get choas

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    • but i cant remember the seed

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    • EPJT OKX2 (Isaac)

      Pick spoon bender. Then reroll prayer card into Dr Fetus. Later you'll find death's touch and sad bombs; then buy chaos (with curse of the blind) and do both boss rush and hush. You'll get most bomb items existing.

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    • alright then

      seed: YYEA G993

      best character : Judas but Isaac is fine

      The Items: ( I had to repeat the run to remember, it took me 14 minutes )

      first floor : Polyphemus, small rock in the marked rock to the left of spawn,cat o nine tails

      second floor: crickets head in the room to the left where you have to battle enemies (You will get a pill but don't pick it up it's tears down), Lil chest, tooth picks (optional = ceremonial robes in the devil deal)

      I'm not going to spoil the rest ;\ but you get the idea. Also save all your keys because until later on you will run out of them.

      This is an Afterbirth seed only ;D

      NOTE: IF PLAYING AS ISAAC YOU CAN PICK UP THE CEREMONIAL DAGGER IN THE DEVIL ROOM ON THE THIRD FLOOR, THIS WORKED FOR ME ON MY SAVE FILE IN WHICH I'VE COMPLETED THE GAME COMPLETELY AND GOT EVERY SINGLE ITEM POSSIBLE FROM CHALLENGES .ETC.

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    • Hgdg hdlh

      Azazel

      Ludo, ball and chain, laser eyes, holy rooms only (shield thing, etc)

      Op as fuuuu

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    • Are any of these compatible with afterbirth+? none seem to work for me.

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    • 83PS PWG9

      soymilk+libra=insane shot speed and damage. Got my first megasatan kill on hard mode

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    • WVGJ OL7W i had 13 hearts by the end of the boss fight on the first floor as issac, dont know if itll be the same for you guys but hey, it was an epic run after that

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    • Opseed wrote: Hgdg hdlh

      Azazel

      Ludo, ball and chain, laser eyes, holy rooms only (shield thing, etc)

      Op as fuuuu

      Totally thought you said Lucio ball at first glance lol

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    • so i know that this is just for seeds and, im trying out a seed and im playing as azazel. I got the iron bar, and im wondering how that works since azazel doesnt have a normal attack like the other characters do... someone tell me please

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    • This definitely qualifies as one of my best runs:

      8JAH 0MCV (Rebirth) - Play as Eden on Normal

      Items:

      Death's Touch (Devil Room, I can't remember which floor, probably Catacombs 1 or 2) + Cricket's Body (Pre-Boss Rush) + SMB Super Fan (Post-Boss Rush) + Guppy Transformation (Tail from Devil Room in Utero 1, Paw in Golden Chest in Catacombs, Head somewhere in Catacombs or Necropolis) + Odd Mushroom (Fire Rate Up, Secret Room) + Iron Bar + X-Ray Vision+ Holy Mantle (Depths 2 Treasure Room).

      Pills:

      Full Health (blue and white), Lemon Party (I remember it was cyan), Amnesia (orange, I think), Luck Up (red and white?), and probably several more I avoided altogether or just can't remember.

      It just feels oddly satisfying to rapid fire a bunch of giant scythes that split into four smaller scythes at your enemies. Effortlessly cleared Boss Rush losing only about 3-4 soul hearts (which is mainly due to my clumsiness with dodging at times) and killed It Lives and Isaac each in 10-15 seconds.

      I apologize for the lack of knowledge of where the items are located, there were so many that I quickly lost track.

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    • @Gorgan67- I'm pretty sure that if you hit someone with an Iron Bar Brimstone Laser as Azazel, it should inflict the what I would like to call "dazed" effect just as if it was a normal concussive tear hitting an enemy.

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    • Yet another one of my best runs:

      ZR6K 68AH (Rebirth) - Play as Azazel on Normal

      Key Items: Small Planet (Chest), Money=Power (Chest), Anti-Gravity (Chest, although the run is probably better without it), Mutant Spider (6-Pip Vault Room in Depths/Necropolis), Proptosis (6-Pip Vault Room in Depths/Necropolis)

      Most of the items I got in this combo came from the 6-pip vault room in Depths/Necropolis. Yes, I got other items like Monstro's Lung (unfortunately no effect in Rebirth), Little Gish, Ball of Tar, Headless Baby, 3 Dollar Bill, etc., but they made no significant contribution to the combo.

      With Anti-Gravity, this basically creates a sort of "Brimstone time bomb". Charge and fire one next to an enemy, and they'll have a few seconds to try to kill you before they get obliterated by four orbiting lasers that each deal double damage. Without Anti-Gravity, well, you get the idea. One-shotted ??? and I think three-shotted It Lives and Isaac.

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    • GBK6 964E - Play as Judas on Normal

      Key Items: Death's Touch, 20/20 (Treasure Room in Necropolis/Depths), Proptosis (Caves/Catacombs Treasure Room), Cricket's Head (Chest), Small Rock, Ouija Board (Treasure Room, can't remember which floor)

      Pills: 2-3 Tears Up, 2-3 Hematenemesis, I can't remember the rest.

      Basically shoots a double flurry of spectral piercing high-damage scythes at your enemies. Cleared Mom, It Lives, Isaac, and ??? in <20 seconds. Cleared Boss Rush in under a minute.

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    • The Forgotten King 1337 wrote:
      GBK6 964E - Play as Judas on Normal

      Key Items: Death's Touch, 20/20 (Treasure Room in Necropolis/Depths), Proptosis (Caves/Catacombs Treasure Room), Cricket's Head (Chest), Small Rock, Ouija Board (Treasure Room, can't remember which floor)

      Pills: 2-3 Tears Up, 2-3 Hematenemesis, I can't remember the rest.

      Basically shoots a double flurry of spectral piercing high-damage scythes at your enemies. Cleared Mom, It Lives, Isaac, and ??? in <20 seconds. Cleared Boss Rush in under a minute.

      i got mutant spider not 20/20

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    • Hey can we make a new format system for the way we post seeds to make it easier .1 rebirth, afterbirth or + .2 difficultly and character .3 example of items and stuff you’ll get .4 warnings, don’t take that devil deal, buy that from shop .5 the seed

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    • 1. Afterbirth Seed

      2. Hard Difficulty on Azazel

      3. Start with Brimstone obviously into Tiny Planet, Book Worm, Spoon Bender, Ceremonial Robes, Pentagram, Safety Pin, Screw 

      4. DO NOT TAKE MOMS KNIFE DEVIL DEAL (I did on my first legit run and it messes the entire brimstone effect)

      (OPTIONAL) Get Smelter after rerolling shop on 2nd or 3rd floor (not sure sorry but its the floor that you get 30 coins without unlocking any other shop prior to this one) heaps of times and then get Left Hand, Petrified Poop, Callus, Lost Cork, Broken Remote, + More

      5. PP2P 7YL4 


      Made an account to post this seed because i failed both times and was really annoyed with myself so hopefully some of you can get some fun out of this one :D

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    • Jcb91606 wrote:
      The Forgotten King 1337 wrote:
      GBK6 964E - Play as Judas on Normal

      Key Items: Death's Touch, 20/20 (Treasure Room in Necropolis/Depths), Proptosis (Caves/Catacombs Treasure Room), Cricket's Head (Chest), Small Rock, Ouija Board (Treasure Room, can't remember which floor)

      Pills: 2-3 Tears Up, 2-3 Hematenemesis, I can't remember the rest.

      Basically shoots a double flurry of spectral piercing high-damage scythes at your enemies. Cleared Mom, It Lives, Isaac, and ??? in <20 seconds. Cleared Boss Rush in under a minute.

      i got mutant spider not 20/20

      I've heard that seeds only roll the same items if the unlocks are the exact same, but I wish I got mutant spider in that run instead of 20/20 :(

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    • 4VA2 F8ZX: Isaac (d6) Hard Mode Items: Reroll 1st item into Polyphemus Tinted rock above spawn contains small rock Mutant spider no reroll All on 1st floor

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    • My Best Run Yet:

      LJ3R CRN1: Play as Azazel on Normal (Rebirth)

      Key Items:

      Basement (Curse of the Labyrinth): Lost Contact and Ludovico Technique

      Caves 1: Polyphemus

      Mom Fight Devil Room: Lump of Coal

      Pre-Boss Rush: Proptosis

      This run (fighting The Lamb, sadly couldn't get Mega Satan), plus boss rush, took me 10 minutes and 53 seconds speedrunning it. Bosses take at most 30-45 seconds to kill, including Satan and The Lamb.

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    • A FANDOM user
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