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IsaacHD Xxx form2 Isaac Rebirth Keeper sprite The Womb is the fourth environment of the game. The player will enter it after killing Mom, but only after they have beaten her once before. It is possible to access the Womb before even killing Mom once, by digging down from Depths II using the We Need To Go Deeper! item. The enemies in this environment are mainly worms and other medical things, and their behaviour often involves disappearing and reappearing across the room (e.g. with the Baby's teleporting or the burrowing behaviour of Para-Bites, Lumps and Fred)

From the chapter The Womb/Utero and onwards, all damage done to Isaac is set to 1 Heart (Full heart). Any type of damage that does 1 heart of damage by default (e.g Bombs) will still do 1 heart of damage in The Womb/Utero and onwards. The only way to avoid it is to use The Wafer item, which sets every type of damage to 1/2 Heart (Half heart).

Rooms

  • 1: The room will always appear once in this floor
  • 2: The room will always appear twice in this floor
  • Possible: There is a chance for this room to appear, usually due to certain criteria being met
  • -: The room cannot appear in this floor.


Rooms with the core game
Rooms The Womb 1 The Womb 2 The Womb XL Note
Regular Rooms 22 - 26 22 - 26 39 - 40 The player must have Wrath of the Lamb installed for The Womb XL to appear.
Treasure room icon Treasure Room - - - From The Womb/Utero and onwards, no more Treasure Rooms will appear.
Shop icon Shop Possible Possible Possible From The Womb/Utero and onwards, no more Shops will appear. But in the Eternal edition there is a very small chance of them spawning.
Secret room icon Secret Room 1 1 1
BossRoomIcon Boss Room 1 1 2 Boss Rooms are always linked in XL floors.
Challegne room icon Challenge Room Possible Possible Possible Will only be generated if Isaac has full health while entering the floor.
Arcade icon Arcade - Possible Possible Only generated when Isaac has 5 Coins upon entering a new floor or part.
Super secret room icon Devil Room Possible Possible Possible If the Devil Room is entered at The Womb 2/The Womb XL, there will be a trapdoor leading to Sheol instead of items being sold for Heart Containers. The trapdoor appears even if the player has not killed It Lives!.
Super secret room icon I AM ERROR Possible Possible Possible Only reachable by using the Telepills, which have a 6.66% chance to teleport Isaac to this room.
Rooms with Wrath of the Lamb
Rooms The Womb 1 The Womb 2 The Womb XL Note
Super secret room icon Super Secret Room 1 1 1
Curse room icon Curse Room Possible Possible Possible
Sacrifice room icon Sacrifice Room Possible Possible Possible
Angel room icon Angel Room Possible Possible Possible If the Angel Room is entered at The Womb 2/The Womb XL, there will be a trapdoor leading to Sheol instead of an item at a pedestal. The trapdoor appears even if the player has not killed It Lives!.
Libary icon Library Possible Possible Possible 5% base chance to spawn, 25% if Isaac is holding a book.
Boss challenge room Boss Challenge Room Possible Possible Possible

Monsters

Monster Description WotL DLC
Sucker
Sucker
Flies slowly towards Isaac, exploding into 4 projectiles in a + formation upon death.
Boil
Boil
Stationary enemy that shrinks upon being hit. Will quickly swell up if not killed in time. Fires multiple short-ranged blood projectiles when fully swollen.
Globin
Globin
Walks towards Isaac, dealing one heart of contact damage. Turns into a pile of goo after taking enough damage, where it can be killed. Will regenerate after a short amount of time if not killed quickly.
Gazing Globin
Globin 2
Quickly walks towards Isaac, dealing one heart of contact damage. Turns into a pile of goo and slides away after taking enough damage, where it can be killed. Will regenerate after a short amount of time if not killed quickly.
Brain
Brain
Crawls around the room, leaving a trail of red Creep that does one heart of damage.
MemBrain
Membrain
Slowly moves around the room, occassionally hopping and firing 8 large blood shots in all directions. Will split into 2 BrainsBrain upon death.
Guts
GutsMonster
Attaches itself to a wall or obstacle, such as a Rock, rolling around the room.
Para-Bite
Parabite
Moves towards Isaac. Can burrow underground and reappear elsewhere.
Fred
Fred
Fires an IPECAC shot at Isaac. Will hop out of the ground and burrow elsewhere, firing 4 blood shots in an X pattern while doing so.
Lump
Lump
Fires 3 fast-moving blood shots at Isaac when he gets in its line of sight. Will burrow underground and reappear elsewhere after firing its shots.
Leech
Leech
Quickly charges towards Isaac when he gets in its line of sight.
Kamikaze Leech
Leech2
Quickly charges towards Isaac when he gets in its line of sight. Explodes with a large blast radius upon death.
Host
Host1
Invulnerable stationary enemy. Raises its head up when Isaac gets close, revealing a fleshy stem that can be damaged. Upon raising its head, it will fire 3 blood shots and lower its head again.
Red Host
Host2
Stationary enemy that can be damaged even when its head is lowered. Fires 5 blood shots instead of 3 when rising, and fires more frequently.
Vis
Vis
Charges up a Brimstone laser when Isaac gets in its line of sight.
Chubber
Chubby Vis
Fires a Little Chubby-like familiar that deals one heart of damage when Isaac gets in its line of sight.
Eye
Eye
Quickly fires a Technology-like laser at Isaac.
Bloodshot Eye
Eye2
Quickly fires a Brimstone-like laser at Isaac.
Dople
Dople1
Copies Isaac's movements, and fires tears at the same time as him.
Evil Twin
Dople 2
Copies Isaac's movements, and fires tears at the same time as him.
Baby
Boby
Fires a single blood shot at Isaac. Can teleport and reappear elsewhere.
Angelic Baby
Angel baby
Fires 3 blood shots at once at Isaac, has much more health than regular Babies.
Minibosses (7 Sins) found in normal rooms:
Wrath
Wrath
Usually paired with another Wrath. Fires Bombs at Isaac that detonate after a short amount of time, in a manner similar to Dr. Fetus.
Sloth
Sloth
Usually paired with another Sloth. Fires IPECAC shots at Isaac, while occasionally spawning ChargersCharger
Envy
Envy
Usually paired with another Envy. Moves around the room slowly at first, and then splits into two faster-moving heads after taking enough damage. These heads will split into two more heads with a smaller size and increased speed after taking enough damage, which will then split into the smallest heads that do not split.
Lust
Lust
Usually paired with another Lust. Moves around the room quickly around the room towards Isaac.
Gluttony
Gluttony
Usually paired with another Gluttony. He has two attacks, an 8-way blood shot and a blood beam attack, similar to that used by Vis.
Bosses found in normal rooms:
Blastocyst
Blastocyst full
Hops around the room, firing 4 large blood shots in a + pattern. Splits into two smaller parts upon taking enough damage, and into an Embyro at the end.
Larry Jr.
Larryjr full
Multi-segmented enemy that quickly crawls around the room, not targeting Isaac. Constantly leaves trails of Poop.
Monstro
260x185-400px-Monstro.svg
Hops towards Isaac. Fires a large volley of blood shots when near Isaac. Can jump high into the ceiling and land somewhere else.
Duke of Flies
Dukeofflies full
Floats around the room, spawning Flies. Spawns multiple Attack Flies and Pooters upon death.
Gemini
Gemini full
Two joined twins that compose 50% of the health bar each. The large twin runs towards Isaac, while the smaller twin fires fast-moving blood shots. The smaller twin will stop firing blood shots upon the larger twin's death, and instead start chasing Isaac.
Fistula
Fistula
Floats around the room diagonally, splitting into smaller, faster versions every time it takes damage. Smallest versions spawn a ChargerCharger when killed.
Chub
Chub Full3
Moves around the room randomly, charging at Isaac if he gets in her line of sight. Constantly spawns ChargersCharger.
Loki
Loki full
Constantly fires 4 blood shots in a plus or cross pattern, and sometimes in all 8 directions at once. Occasionally teleports around the room. Can spawn Boom FliesBoomfly.
Peep
Peep Full
Slowly moves around the room, firing 6 urine shots in all directions. Can jump towards the ceiling and drop down elsewhere, like Monstro. Can release yellow Creep occasionally. Upon reaching 66% and 33% health respectively, an invulnerable eye will pop out that flies around the room diagonally like Boom Flies.

Bosses

Differences from previous floors

  • Blood donation machines take away a whole heart instead of half. They can still be used twice for one heart by quickly using them again during Isaac's invincibility period after taking damage. This can be done because taking a full heart of damage gives Isaac a longer invincibility period.
  • Two of Seven Deadly Sins can be encountered in one room multiple times.

Room-layouts

Related Achievements

Judasfez "Judas' Fez" - Complete The Womb 2 once.
Noose "The Noose" - Complete The Womb 2 two times.
Nail "The Nail" - Complete The Womb 2 three times.
Quarter "The Quarter" - Complete The Womb 2 four times.
Fetus "The Fetus" - Complete The Womb 2 five times.
Everythingsterrible "Everything's Terrible!" - Complete The Womb 2 six times.
Wafer "The Wafer" - Complete The Womb 2 seven times.
Moneypower "Money = Power" - Complete The Womb 2 eight times.
Itlives "It Lives!" - Complete The Womb 2 nine times.
Unknown "???" - Complete The Womb 2 ten times.
Mamasboy "Mama's Boy" - Complete The Womb without taking damage.

Chapters
Chapter 1 Chapter 2 Chapter 3 Chapter 4 Chapter 5 Chapter 6

The ChestWrath of the Lamb DLC

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