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The Virus is a passive item.

A syringe with a red substance in it.

Effects[]

Isaac becomes pale with signs of sickness on his body, and gets bumps and markings.

Touching enemies will inflict them with poison, as well as deal a large amount of damage.

The Virus also decreases Speed by 0.1, however this reduction in speed does not stack with the speed down from Odd Mushroom (Large).

Synergies[]

  • Book Of Shadows - Turns you invincible with the poison touch effect still working while invincible.
  • The Polaroid - While invincible, allows Isaac to poison enemies without taking damage.
  • Celtic Cross - If invincibility triggers, poison touch will be effective against many enemies.
  • My Little Unicorn/The Gamekid - Poison touch overrides their 40 damage hit with its 30 damage hit (and poison). Otherwise it doesn't change what they do.
  • The Nail - The contact damage of The Virus overrides the contact damage of The Nail.
  • Mom's Bra/Mom's Pad - Contact damage on the player is disabled during the effect of either active. This allowing for safer application of the contact damage and poison damage of The Virus.
  • Best Friend - The brief window of invincibility frames when casting Best Friend allow for a free application of The Virus.

Trivia[]

  • The substance in the syringe is probably infected blood, which is an incredibly easy way to contract STDs.
  • Lust is a recolor of Isaac with The Virus graphic applied. Lust also has a chance to drop The Virus upon death.
    • This may be why it's thought to be an STD.

Bugs[]

  • The Virus, like all other contact damage items, cannot inflict contact damage or poison damage to Hearts or Mom's Heart/It Lives, but can do so to other enemies that don't deal contact damage to the player.

Related Achievements[]

Items
Passive Items Tear Modifiers: The Inner EyeSpoon BenderMy ReflectionSkatoleCube of MeatCupid's ArrowDr. FetusMom's EyeWiggle WormTechnologyChocolate MilkLoki's HornsLittle ChubbySpider's BiteThe Common ColdThe ParasiteMom's ContactsMom's KnifeOuija BoardBrimstoneA Lump of Coal

(Wrath of the Lamb DLC: IPECACTough LoveTechnology 2Mutant SpiderEpic FetusPolyphemusSacred Heart)

Stat Ups: The Sad OnionMax's HeadNumber OneBlood of the MartyrMagic MushroomRoid RageRaw LiverLunchDinnerDessertBreakfastRotten MeatWooden SpoonThe BeltMom's UnderwearMom's HeelsMom's LipstickWire Coat HangerStevenPentagramThe MarkGrowth HormonesMini MushroomThe PactSmall RockSuper BandageRobo-BabyLittle C.H.A.D.Little GishLittle SteveThe RelicThe HaloMoney Equals PowerBlood BagOdd Mushroom (Thin)Odd Mushroom (Large)Whore Of BabylonBucket Of Lard
(Wrath of the Lamb DLC: StigmataSpeed BallChemical PeelBloody LustCat-O-Nine-TailsStem CellsTooth PicksSMB Super Fan!MEAT!Magic 8 BallSqueezyJesus Juice)

Familiars and Orbitals: Brother BobbyHalo Of FliesDistant AdmirationSister MaggyGuardian AngelDemon BabyDead BirdForever AloneSack Of PenniesBomb Bag
(Wrath of the Lamb DLC: Bum FriendThe PeeperGhost BabyHarlequin BabyDaddy LonglegsSacrificial DaggerRainbow BabyHoly WaterGuppy's Hair BallAbel)

Others: 1UPThe VirusLess Than ThreeSkeleton KeyA DollarA QuarterBoom!TranscendenceThe CompassPHDRosaryXRay VisionLucky FootMagnetoTreasure MapThe LadderCharm Of The VampireThe BatterySteam SaleDead CatLord Of The PitSpelunker HatMr. MegaThe Wafer9 VoltBobby-Bomb
(Wrath of the Lamb DLC: Guppy's TailMom's PurseBob's CursePageant BoyScapularInfestationThe MulliganHabitSpirit Of The NightAnkhCeltic CrossMitreFateThe Black BeanHoly GrailDead DovePyro3 Dollar BillMom's Coin PurseBox)

Activated Items Base Items: The PoopMr. BoomTammy's HeadMom's BraKamikazeMom's PadBob's Rotten HeadTeleport!My Little UnicornYum HeartDoctor's RemoteShoop Da Whoop!Lemon MishapThe HourglassThe NailWe Need To Go Deeper!Deck of CardsMonstro's ToothThe GamekidMom's Bottle of PillsThe DiceThe Pinking ShearsThe BeanDead Sea ScrollsRazor BladeForget Me NowA Pony

(Wrath of the Lamb DLC: Guppy's PawIV BagBest FriendRemote DetonatorGuppy's HeadPrayer CardNotched AxeCrystal BallCrack The SkyThe CandleD20Spider ButtDad's KeyPortable SlotWhite PonyBlood Rights)

Books: The BibleThe Book of BelialThe NecronomiconBook Of RevelationsBook of ShadowsAnarchist CookbookThe Book Of SinMonster Manuel
(Wrath of the Lamb DLC: Telepathy for Dummies)

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