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Not to be confused with the passive item, The Black Bean.
A small brown bean. Goes by the name Karen sometimes.
Upon use, releases gas that poisons any enemies within close range (1 square in all directions).
- Orbitals such as Halo Of Flies, Cube Of Meat, Sacrificial Dagger and Guardian Angel, and the Pretty Fly Pill allow Isaac to get closer to enemies without getting hit as often, making for more effective use of this item.
- It is identical in effect to a Bad Gas Pill.
- The Black Bean is a passive version of this item. However, for it to activate the player must be hit and take damage from an enemy.