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No, I got all three at once. There was some sort of item in the middle of the room -- can't remember what it was, or what achievement it unlocked -- and all three waves arrived in one big heap. Mercifully, this occurred pretty early in the playthrough, so it was (if I recall correctly) Chargers, Spities, and Hoppers rather than Knights or anything equally life-threatening. Still took a lot of damage getting out of there.

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