- For other uses, see Keeper (disambiguation).
They look nearly identical to Greed with random facial features. They can be noticeably seen either hanged by the noose or just sitting on the floor.
Destroying them with explosive items (such as bombs) will cause them to yield rewards.
- One of the Shopkeeper's face (image number 8 from the infobox) is identical to the Forever Alone face meme.
|The Binding of Isaac|
They cannot be destroyed by bombs or any explosion-related items.
Note that every time when entering and re-entering the room where the Shopkeeper's at, their appearance keep changing.
|Isaac • Magdalene • Judas • Cain • Eve • Samson • ??? • Eden • Lazarus • The Lost • Lilith • Keeper • Apollyon • Satoru Iwata|
|Babies • Beggar • Devil Beggar • Key Beggar • Shell Game Beggar • Bomb Bum • Shopkeeper • Others|
|Old Man Keeper|