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Pestilence

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IsaacHDIsaac Rebirth

Pestilence

BC Pestilence

Boss Pestilence


Official artwork by Edmund McMillen
Statistics
Type
Health
Damage
{{{type}}}
{{{health}}}
{{{damage}}}
Floor(s)
The Caves
Catacombs
Related Bosse(s)
Famine

War
Death
Conquest

Headless Horseman
Effective Item(s)
N/A
Dropped Item(s)
Cube of Meat

Pestilence, one of the four Horsemen of the Apocalypse, is a boss which can be encountered instead of a traditional boss in the Caves and Catacombs once the player has beaten the game for the first time (killed Mom).

Pestilence is guaranteed to be the boss when Book Of Revelations is used in the Caves or the Catacombs (unless the Headless Horseman appears in his place).

Description

He is a bloated, diseased, and zombie-like being with green colors that lazily leans back on his rotting steed as it carries him around.

Behavior

Pestilence has two main phases:

Phase 1

Pestilence

  • Like Sloth, he fires a lobbed projectile similar to IPECAC, which explodes on contact, and does one heart of damage only. As Well, Pestilence says "hey". It also leaves a pool of green creep upon exploding.
  • His movement leaves a large, green creep.
  • He summons Chargers and Spitties periodically.

Phase 2

Pestilence headless

  • After reducing his health to one half, his head is destroyed, leaving his body still mounted on his horse. It still leaves the green puddles of creep wherever it goes and fires the green bombs more rapidly. Also, the horse begins to summon red and black Flies, with the same coughing sound as the Hive (to compensate for the fact that he is no longer able to summon Chargers and Spitties during this phase).

Champion Variants

Pestilence white
White

Phase 1 shoots 6 white bullets and summons Trites. Also leaves a white creep (similar to the Widow's) that slows down Isaac if stepped on.

Phase 2 summons a small Spider and shoots 6 blood bullets.

Trivia

  • Pestilence quote often erroneously replaces Conquest in popular culture. The actual text of the Revelation describes Conquest as the first of the four horsemen of the Apocalypse (described as a rider with a bow on a white horse (Rev. 6:2)) and makes no mention of Pestilence.
    • "A Forgotten Horseman" achievement might be a reference to the fact that Conquest is often forgotten in popular culture.
  • Pestilence is the only horseman in the game that doesn't grab his horse. (Excluding the Headless Horseman)
  • Pestilence means a fatal epidemic disease

Bugs

  • Occasionally, regular Pestilence will fire three of its shots at once, like a Super Sloth. It can fire as many as 8 of these shots in a rapid succession.
    • Mostly of the time this happens Pestilence will not show its animation.
  • Occasionally, as soon as the battle with Pestilence begins, he will fire a single IPECAC shot towards Isaac while he is in the doorway without showing his animation.
  • Pestilence may glitch into the wall if you push him hard enough, rendering the fight impossible.
  • Pestilence can take poison damage (via The BeanThe Common ColdBob's Rotten HeadThe Virus, and Bob's Curse), but his sprite will not change color.
  • If killed by the white Champion Pestilence's shots, Isaac's Last Will will state that he was killed by a Gusher.

Gallery

Videos

The Harbingers Related
Famine Pestilence War Death Conquest Headless ingame
Famine Pestilence War Death Conquest Headless Horseman


Bosses
Regular Bosses
Blastocyst button

Blastocyst
Brownie
Chub button

Chub
Daddy Long Legs button

Daddy Long Legs
Dangle
Dark One button

Dark One
Dingle button

Dingle
Duke of Flies button

The Duke of Flies
Fallen button

The Fallen
Fistula button

Fistula
Gemini button

Gemini
Gurdy button

Gurdy
Gurdy Jr button

Gurdy Jr.
Gurgling button

Gurglings
Haunt button

The Haunt
Larry Jr button

Larry Jr.
Little Horn
Loki button

Loki
Mama Gurdy button

Mama Gurdy
Mask of Infamy button

Mask of Infamy
Mega Fatty button

Mega Fatty
Mega Maw button

Mega Maw
Monstro button

Monstro
Mr Fred button

Mr. Fred
Peep button

Peep
Pin button

Pin
Polycephalus button

Polycephalus
Rag Man
Scolex button

Scolex
Turdlings
Widow button

Widow
Posthumous Bosses
Adversary button

The Adversary
Blighted Ovum button

The Blighted Ovum
Bloat button

The Bloat
Cage button

The Cage
Carrion Queen button

Carrion Queen
The Forsaken
The Frail
Gate button

The Gate
Hollow button

The Hollow
Husk button

The Husk
Lokii button

Lokii
Monstro II button

Monstro II
Teratoma button

Teratoma
The Stain
Wretched button

The Wretched
Alternative Bosses
CHAD button

C.H.A.D.
Gish button

Gish
Sister Vis button

Sisters Vis
Steven button

Steven
Triachnid button

Triachnid
Harbingers
Conquest button

Conquest
Death button

Death
Famine button

Famine
Headless Horseman button

Headless Horseman
Pestilence button

Pestilence
War button

War
Final Bosses
XXX button

???
Hush
Isaac button

Isaac
It Lives button

It Lives
Lamb button

The Lamb
Mega Satan button

Mega Satan
Mom button

Mom
Mom's Heart button

Mom's Heart
Satan button

Satan
Ultra Greed
Minibosses
Seven Deadly Sins
Envy button

Envy
Gluttony button

Gluttony
Greed button

Greed
Lust button

Lust
Pride button

Pride
Sloth button

Sloth
Wrath button

Wrath
Seven Super Deadly Sins
Envy button

Super Envy
Super Gluttony button

Super Gluttony
Super Greed button

Super Greed
Super Lust button

Super Lust
Super Pride button

Super Pride
Super Sloth button

Super Sloth
Super Wrath button

Super Wrath
Ultra Pride button

Ultra Pride
Angels / Demons
Krampus button

Krampus
Angel button

Gabriel
Angel button

Uriel
Angel button

Fallen Angels
LEGENDS: The Binding of Isaac bosses are yellow. Wrath of the Lamb bosses are teal. Rebirth bosses are orange. Afterbirth bosses are crimson. Afterbirth † bosses are violet.

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