Isaac Rebirth

Oobs are stronger enemies added to The Binding of Isaac: Rebirth. They first appear in Chapter 4.


It has a similar AI to Harbingers (Famine and War). When Isaac is not horizontal to it, it spawn 2 Brains. When Isaac is horizontal to it, it does a very fast charge that can cover the entire room at once.


  • Oobs are also enemies from another one of Edmund's games, Super Meat Boy.[1]
  • Oobs are one of the few non-boss enemies to have over 100 health points.
  • Oobs are the only enemies to have a Harbinger-styled charge attack. Same apply to their variant Black Maws.


Black FlyAttack FlyMoterEternal FlyPooterFat FlyBoom FlyRed Boom FlyDrowned Boom FlySuckerSpitDart FlySwarm FlyRing FlyLevel 2 FlyFull FlyHush FlyBall of FliesSpiderBig SpiderTriteRaglingRag TriteLevel 2 SpiderTicking SpiderBaby Long LegsCrazy Long LegsWall CreepBlind CreepRage CreepPara-BiteCod WormScarred Para-BiteRound WormNightcrawlerRoundyUlcerMaggotChargerSpittyConjoined SpittyDrowned ChargerGrubClottyClotMega ClottyLeechKamikaze LeechHoly Leech
BoilGutSackBlue BoilHostRed HostWall HuggerSlidePokyStone GrimaceVomit GrimaceGaping MawTurret GrimaceBrimstone Grimace
MulliganMulligoonMulliboomHiveSwarmerNestDrowned HiveHopperFlaming HopperLeaperPacerGusherSplasherGaperFrowning GaperGurgleMr. MawFlaming GaperCyclopiaSkinnyRottyNullGreed GaperBlue GaperSwingerHorfPsychic HorfGlobinGazing GlobinBlack GlobinDank GlobinKnightSelfless KnightFloating KnightBone KnightBonyBlack BonyFattyFlaming FattyConjoined FattyBlue Conjoined FattyPale FattyKeeperHangerVisDouble VisChubberCage VisScarred Double VisHomunculusBegottenDopleEvil Twin
Body parts
Mask + HeartBrainMemBrainGutsMama GutsEyeBloodshot EyeMom's HandDead Mom's HandScarred GutsNerve EndingStone Eye
DipCorn DipBrown DipSquirtDank SquirtDinga
MawRed MawPsychic MawDeath's HeadDank Death's HeadFlesh Death's HeadLil' HauntWizoobRed GhostOne ToothFat BatTumorPsy TumorCamillo Jr.BabyAngelic BabyImpDukieOobBlack Maw
FredLumpEmbryoB. Licker