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Monsters

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Monsters are many creatures encountered throughout the game.

Most monsters (with few exceptions) will damage Isaac by either touching him or shooting him with shots. Along with normal varieties of monsters, Champion versions of monsters can be found lurking about. These monsters are often like normal monsters, but have a color tint or size change and drop basic Pick Ups (or rarely, a Chest) upon death. There are also Champion version of Bosses.

Monster List

Monster Description WotL DLC
Black Fly
Fly
Tiny black flies that do not hurt Isaac upon touch.
Attack Fly
CUSTOMredfly
Red Flies that follow Isaac and deal touch damage.
Moter
Moters
Follows Isaac, similar to Attack Flies. Will split into 2 Attack FliesCUSTOMredfly upon death.
Eternal Fly
White fly
Invulnerable Fly that circles Corny PoopNuttypoop, Holy LeechesHoly leech or HangersHang man.
Pooter
Pouter
Slow-moving flies that fire single blood shots at Isaac. Pooters do not deal touch damage.
Fat Fly
Superpooter
Alternate version of PootersPouter. Fires 2 shots in a V-formation and does not deal touch damage.
Boom Fly
Boomfly
Flies around the room diagonally, dealing touch damage and exploding with a large blast radius upon death.
Red Boom Fly
Spitfly
Flies around the room diagonally, dealing touch damage and exploding into 6 directional blood shots upon death.
Sucker
Sucker
Flies slowly towards Isaac, exploding into 4 projectiles in a + formation upon death.
Spit
Puffer
Flies slowly towards Isaac, exploding into an IPECAC shot upon death which targets other Spits in the room, or Isaac.
Spider
Black spider
Moves erratically around the room, damaging Isaac by touch.
Big Spider
Big spider
Moves erratically around the room, splitting into two SpidersBlack spider upon death.
Trite
Spider hopper
Quickly jumps towards Isaac with high distance.
Boil
Boil
Stationary enemy that shrinks upon being hit. Will quickly swell up if not killed in time. Fires multiple short-ranged blood projectiles when fully swollen.
Gut
Green boil
Stationary enemy that shrinks upon being hit. Will quickly swell up if not killed in time. Fires an IPECAC shot at Isaac when fully swollen.
Sack
White boil
Stationary enemy that shrinks upon being hit. Swells up slower than Guts and Boils. Spawns a SpiderBlack spider when fully swollen.
Walking Boil
Walking boil
Mobile Boil that cannot shrink, but has a finite amount of health. Fires short-ranged blood shots with varying sizes at a reduced fire rate.
Walking Gut
Walking green boil
Mobile Gut that cannot shrink, but has a finite amount of health. Fires IPECAC shots at a reduced fire rate.
Walking Sack
Walking cocoon
Mobile Sack that cannot shrink, but has a finite amount of health. Spawns SpidersBlack spider.
Mulligan
Mulligan
Harmless enemy that walks around the room, avoiding Isaac. Will spawn multiple fliesFly upon death.
Mulligoon
Mulligoon
Harmless enemy that walks around the room, avoiding Isaac. Will drop a Troll BombTroll bomb upon death.
Mulliboom
Mulliboom
Walks towards Isaac, exploding with a large blast radius upon death or upon touching Isaac. The explosion does a half-heart of damage instead of the regular full heart.
Hive
Hive
Walks around the room, avoiding Isaac while spawning Attack FliesCUSTOMredfly. Spawns a large number of FliesFly upon death.
Swarmer
Swarmhead
Slowly floats around the room, spawning a Pooter upon taking damage. Spawns a large number of Flies upon death.
Hopper
Hopper
Jumps around the room slowly, damaging Isaac by touch.
Flaming Hopper
FHopper
Jumps around the room quickly, covering a large distance, similar to Trites.Spider hopper
Leaper
Leaper
Jumps around the room quickly, but not as fast as F. Hoppers. Occasionally jumps high into the air, dropping down elsewhere while firing 4 blood shots in a plus pattern.
Pacer
Pacer
Walks aimlessly around the room. Usually spawned after killing a Gaper/Frowning Gaper.Gaper
Gusher
Gusher
Walks aimlessly around the room, firing extremely short-ranged blood projectiles from its head. Usually spawned after killing a Gaper/Frowning Gaper.Gaper
Gaper
Gaper
Walks towards Isaac, dealing contact damage. Usually turns into a PacerPacer or GusherGusher upon death.
Frowning Gaper
Frowninggaper
Walks towards Isaac, dealing contact damage. Usually turns into a PacerPacer or GusherGusher upon death.
Gurgle
Gurgle
Slowly walks towards Isaac, firing short-ranged IPECAC shots at him. Has much more health than regular Gapers.
Mr. Maw
Shape4336
Walks towards Isaac, quickly launching its head, still attached to its body by a cord. Turns into a MawMaws or PacerPacer upon death.
Horf
Horfs
Stationary enemy that fires medium ranged blood shots at Isaac.
Maw
Maws
Floats towards Isaac, firing fast-moving blood shots.
Red Maw
Redmaw
Floats towards Isaac faster than regular Maws, exploding into 4 blood shots in a plus pattern upon death. Does not fire any shots.
Psychic Maw
Psychicmaw
Alternate version of a Maw, has an Eternal FlyWhite fly circling it. Fires large, purple homing shots at Isaac.
Globin
Globin
Walks towards Isaac, dealing one heart of contact damage. Turns into a pile of goo after taking enough damage, where it can be killed. Will regenerate after a short amount of time if not killed quickly.
Gazing Globin
Globin 2
Quickly walks towards Isaac, dealing one heart of contact damage. Turns into a pile of goo and slides away after taking enough damage, where it can be killed. Will regenerate after a short amount of time if not killed quickly.
Knight
Knights
Moves erratically around the room. Can only be damaged from behind.
Selfless Knight
Alternative knight
Moves erratically around the room, charging at Isaac at very high speed. Can only be damaged from behind.
Mask + Heart
Mask Heart
Invulnerable mask with a slow-moving Heart. Functions similarly to a Knight. The Heart fires 4 blood shots in a plus pattern when Isaac gets near. Killing the Heart will automatically kill the Mask.
Clotty
Clotty
Moves around the room, firing 4 blood shots in a plus pattern.
Clot
Clot2
Moves around the room, firing 4 tar shots in an X pattern.
I. Blob
Blockade
Moves around the room, firing 8 shots in all directions.
Maggot
Maggot
Aimlessly moves around the room, damaging Isaac by contact.
Charger
Charger
Slowly moves around the room, charging at Isaac when he gets in its line of sight.
Spitty
Spity
Slowly moves around the room, firing a single long-ranged blood shot when Isaac gets in its line of sight.
Brain
Brain
Crawls around the room, leaving a trail of red Creep that does one heart of damage.
MemBrain
Membrain
Slowly moves around the room, occasionally hopping and firing 8 large blood shots in all directions. Will split into 2 BrainsBrain upon death.
Guts
GutsMonster
Attaches itself to a wall or obstacle, such as a Rock, rolling around the room.
Mama Guts
Big guts
Slowly moves around the room, occasionally hopping and firing 8 large blood shots in all directions. Will split into 2 GutsGutsMonster upon death.
B. Licker
Centipede
Attaches itself to other B. Lickers, erratically moving around the room, similar to Larry Jr.
Para-Bite
Parabite
Moves towards Isaac. Can burrow underground and reappear elsewhere.
Fred
Fred
Fires an IPECAC shot at Isaac. Will hop out of the ground and burrow elsewhere, firing 4 blood shots in an X pattern while doing so.
Lump
Lump
Fires 3 fast-moving blood shots at Isaac when he gets in its line of sight. Will burrow underground and reappear elsewhere after firing its shots.
Leech
Leech
Quickly charges towards Isaac when he gets in its line of sight.
Kamikaze Leech
Leech2
Quickly charges towards Isaac when he gets in its line of sight. Explodes with a large blast radius upon death.
Holy Leech
Holy leech
Quickly charges towards Isaac when he gets in its line of sight. Explodes with a large blast radius upon death. Has an Eternal FlyWhite fly circling it.
Host
Host1
Invulnerable stationary enemy. Raises its head up when Isaac gets close, revealing a fleshy stem that can be damaged. Upon raising its head, it will fire 3 blood shots and lower its head again.
Red Host
Host2
Stationary enemy that can be damaged even when its head is lowered. Fires 5 blood shots instead of 3 when rising, and fires more frequently.
Vis
Vis
Charges up a Brimstone laser when Isaac gets in its line of sight.
Double Vis
Vis Fio
Charges up a Brimstone laser which fires from both sides when Isaac gets in its line of sight.
Chubber
Chubby Vis
Fires a Little Chubby-like familiar that deals one heart of damage when Isaac gets in its line of sight.
Poky
Poky
Moves around the room, damaging Isaac by contact.
Slide
Slide
Quickly slides towards Isaac when he gets in front of it.
Eye
Eye
Quickly fires a Technology-like laser at Isaac.
Bloodshot Eye
BloodshotEye
Quickly fires a Brimstone-like laser at Isaac.
Dople
Dople1
Copies Isaac's movements, and fires tears at the same time as him.
Evil Twin
Dople 2
Copies Isaac's movements, and fires tears at the same time as him.
Embryo
Embryo
Aimlessly hops around the room, damaging Isaac by contact damage.
Baby
Boby
Fires a single blood shot at Isaac. Can teleport and reappear elsewhere.
Angelic Baby
Angel baby
Fires 3 blood shots at once at Isaac, has much more health than regular Babies.
Keeper
Keeper
Hops around the room, firing 2 blood shots in a V formation at Isaac.
Hanger
Hang man
Floats around the room, firing 3 blood shots at Isaac. Has an Eternal FlyWhite fly circling it.
Stone Grimace
Turret
Stationary and invulnerable monster that fires a fast-moving blood shot at Isaac. Stops firing when room is cleared.
Vomit Grimace
VomitTurret
Stationary and invulnerable monster that fires an IPECAC shot at Isaac. Stops firing when room is cleared.

Monster List by Floor

The Basement

Cellar

The Caves

Catacombs

The Depths

Necropolis

The Womb

Bosses up to the Caves
A pair of complete Blastocysts or 4 'second stage' Blastocysts may spawn.

Utero

Bosses up to the Caves
A pair of complete Blastocysts or 4 'second stage' Blastocysts may spawn.

Sheol

Two Greeds and a whole Fistula.
All bosses up to the Depths as well as Death, The Fallen, Headless Horseman, Loki (commonly 2) and Lokii
Some bosses will appear in pairs of themselves, such as Gemini.
Gurdy will not appear.
*Rarely monsters from early levels, such as a non-aggressive fly will spawn in rooms by themselves. This might be a bug.

Cathedral

All bosses up to the Depths as well as the Headless Horseman, Loki (commonly found as a pair, complete with Poky) and Lokii

Monster replacements

Some monsters in the Binding of Isaac are randomly replaced by similar counterparts. These can either be "champion" versions that are recolored or completely different enemies with modified attacks.

Champion Enemies

Normal enemies can be recolored to become champion enemies, which by default have twice as much HP as their normal counterparts. Similarly, some champion enemies are able to deal full heart damage regardless of the level. Champion enemies will always drop a free pickup when killed.

Enemy Variants

These variants may replace normal enemies in a room

Some variants will additionally count as champion enemies if encountered on certain floors. For example, Bloodshot Eyes, Selfless Knights, Kamikaze/Holy Leeches and the Evil Twin can be considered champions when encountered in the Womb or earlier and will drop a pickup when killed.

Replacement/Variation Chart

Mulligan may be replaced by Mulligoon or Mulliboom

Hopper may be replaced by Spider hopper

Turretmay be replaced by VomitTurret

Dople1 may be replaced by Dople 2

Eye may be replaced by BloodshotEye

Leech may be replaced by Leech2 or Holy leech

Maws may be replaced by Redmawor Psychicmaw


Host1 may be replaced byHost2

Vis may be replaced by Vis Fio or Chubby Vis

Boomfly may be replaced by Spitfly

Pouter may be replaced by Superpooter

Pacer may be replaced by Gusher

Knights may be replaced by Alternative knight

Clotty may be replaced by Clot2 or Blockade

Membrain may be replaced by Big guts

Gaper may be replaced with Frowninggaper

Globin may be replaced with Globin 2

Boby may be replaced with Angel baby

Gallery

Start a Discussion Discussions about Monsters

  • Same monsters on a floor

    • Seeing as Rebirth is coming, I'm trying to max the achievements on the old game. However, I've started to notice that the variety of monsters ...
  • Three things.

    6 messages
    • Do you people never read dates? This thread is a month old, and I doubt that guy is going to read it.
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