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Monster Manual is an unlockable activated item.

It is a book with a centaur, horse, and a dragon on its cover.

Effects[]

Upon activation, Satan's laugh will be heard and a random Familiar (even locked familiars) will spawn and help Isaac for the current room. Can spawn one of the following:

Synergies[]

  • Combined with items such as the 9 Volt, Habit, etc. can allow Isaac to have an army of familiars following him. Using this in a boss room can cause the boss to lose health very rapidly.

Trivia[]

  • The item and its graphics are both references to the D&D Monster Manual.
  • Its presence is related to the statement that D&D is a gateway to Satanism.
  • The secret pop-up for this item misspells Monster Manual as "Monster Manuel".

Bugs[]

  • More than 3 orbitals may be active as a result using this item; this may have been done to avoid deleting old orbitals by accident, or could have been simply overlooked.
  • Will spawn "undefined," if too many familiars are present on screen.  
Items
Passive Items Tear Modifiers: The Inner EyeSpoon BenderMy ReflectionSkatoleCube of MeatCupid's ArrowDr. FetusMom's EyeWiggle WormTechnologyChocolate MilkLoki's HornsLittle ChubbySpider's BiteThe Common ColdThe ParasiteMom's ContactsMom's KnifeOuija BoardBrimstoneA Lump of Coal

(Wrath of the Lamb DLC: IPECACTough LoveTechnology 2Mutant SpiderEpic FetusPolyphemusSacred Heart)

Stat Ups: The Sad OnionMax's HeadNumber OneBlood of the MartyrMagic MushroomRoid RageRaw LiverLunchDinnerDessertBreakfastRotten MeatWooden SpoonThe BeltMom's UnderwearMom's HeelsMom's LipstickWire Coat HangerStevenPentagramThe MarkGrowth HormonesMini MushroomThe PactSmall RockSuper BandageRobo-BabyLittle C.H.A.D.Little GishLittle SteveThe RelicThe HaloMoney Equals PowerBlood BagOdd Mushroom (Thin)Odd Mushroom (Large)Whore Of BabylonBucket Of Lard
(Wrath of the Lamb DLC: StigmataSpeed BallChemical PeelBloody LustCat-O-Nine-TailsStem CellsTooth PicksSMB Super Fan!MEAT!Magic 8 BallSqueezyJesus Juice)

Familiars and Orbitals: Brother BobbyHalo Of FliesDistant AdmirationSister MaggyGuardian AngelDemon BabyDead BirdForever AloneSack Of PenniesBomb Bag
(Wrath of the Lamb DLC: Bum FriendThe PeeperGhost BabyHarlequin BabyDaddy LonglegsSacrificial DaggerRainbow BabyHoly WaterGuppy's Hair BallAbel)

Others: 1UPThe VirusLess Than ThreeSkeleton KeyA DollarA QuarterBoom!TranscendenceThe CompassPHDRosaryXRay VisionLucky FootMagnetoTreasure MapThe LadderCharm Of The VampireThe BatterySteam SaleDead CatLord Of The PitSpelunker HatMr. MegaThe Wafer9 VoltBobby-Bomb
(Wrath of the Lamb DLC: Guppy's TailMom's PurseBob's CursePageant BoyScapularInfestationThe MulliganHabitSpirit Of The NightAnkhCeltic CrossMitreFateThe Black BeanHoly GrailDead DovePyro3 Dollar BillMom's Coin PurseBox)

Activated Items Base Items: The PoopMr. BoomTammy's HeadMom's BraKamikazeMom's PadBob's Rotten HeadTeleport!My Little UnicornYum HeartDoctor's RemoteShoop Da Whoop!Lemon MishapThe HourglassThe NailWe Need To Go Deeper!Deck of CardsMonstro's ToothThe GamekidMom's Bottle of PillsThe DiceThe Pinking ShearsThe BeanDead Sea ScrollsRazor BladeForget Me NowA Pony

(Wrath of the Lamb DLC: Guppy's PawIV BagBest FriendRemote DetonatorGuppy's HeadPrayer CardNotched AxeCrystal BallCrack The SkyThe CandleD20Spider ButtDad's KeyPortable SlotWhite PonyBlood Rights)

Books: The BibleThe Book of BelialThe NecronomiconBook Of RevelationsBook of ShadowsAnarchist CookbookThe Book Of SinMonster Manuel
(Wrath of the Lamb DLC: Telepathy for Dummies)

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