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Brain

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IsaacHDIsaac Rebirth

Brain
Brain

In-game sprite
Statistics
Type
Health
Damage
Brain
???
Full heart
Floor(s)
The Depths
The Womb
Utero
Related Monster(s)
MemBrain

Brains are enemies appearing in The Binding of Isaac and the Rebirth remake. They can commonly be found in The Depths and The Womb.

Behavior

Brains move around the room slowly, leaving a trail of red Creep that does one full heart of damage to Isaac. They are relatively weak on their own, but can quickly corner Isaac when fought in groups.

Trivia

  • In the original game, Brains use to flash in color red for few seconds every time while moving. However, they no longer does so in Rebirth.
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