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Mega Fatty

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Isaac RebirthKeeper sprite

Mega Fatty
Mega Fatty
Official artwork by Edmund McMillen.
The Caves
Related Bosse(s)
The Cage
Effective Item(s)
Speed-increasing items, such as the Wooden Spoon
Dropped Item(s)
Standard Boss Items

Mega Fatty is one of the bosses added in The Binding of Isaac: Rebirth. As his name implies, he is based off the Fatty enemy.


Mega Fatty is a large, bloated humanoid with beady eyes streaming bloody tears. He has one tooth at the bottom of his blood-stained mouth. Furthermore, he has stubby arms.


Mega Fatty will not move or chase the player, unless jumping up and landing in the place where Issac is. (similar to Monstro's cycle of attack) The player must be wary, as his 'pooping' attacks are long range and also tracking. He is usually easy to kill after one or more encounters with him.

Mega Fatty has a number of different attacks:

  • Mega Fatty can hold, and fart, pooping out a Squirt . He may poop out more than one.
  • Mega Fatty can hold, and fart, also pooping out an array of "poop" bullets towards Isaac.
  • Mega Fatty jumps up, then lands in the position Issac is, leaving red creep around where he landed.
  • Mega Fatty opens his mouth, and then poops out an array of homing brown bullets towards Issac. The bullets will keep on shooting at Isaac for a while, then will stop.

Champion Variants

In the The Binding of Isaac: Afterbirth expansion, Mega Fatty has two different champion variants.


Coming soon.


Coming soon.


  • He may be based (or similar to) the boss Gluttony, one of the seven deadly sins.
    • Oddly enough, during his death animation, Mega Fatty's face look eerily similar to Gluttony.


Regular Bosses
BlastocystBrownieChubDaddy Long LegsDangleDark OneDingleDuke of FliesThe FallenFistulaGeminiGurdyGurdy Jr.GurglingsThe HauntLarry Jr.Little HornLokiMama GurdyMask of InfamyMega FattyMega MawMonstroMr. FredPeepPinPolycephalusRag ManScolexTurdlingsWidow
Posthumous Bosses
The AdversaryThe Blighted OvumThe BloatThe CageCarrion QueenThe ForsakenThe FrailThe GateThe HollowThe HuskLokiiMonstro IITeratomaThe StainThe Wretched
Alternative Bosses
ConquestWarFamineDeathPestilenceHeadless Horseman
Final Bosses
???HushIsaacIt LivesThe LambMega SatanMomMom's HeartSatanUltra Greed
Sisters Vis
Seven Deadly Sins
Seven Super Deadly Sins
Super EnvySuper GluttonySuper GreedSuper LustSuper PrideSuper SlothSuper WrathUltra Pride
Angels / Demons
KrampusGabrielUrielFallen Angels

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