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Items are an integral part of gameplay in The Binding of Isaac. They modify a character's stats, or grant or modify abilities, among many other things.

Items in general are classified into a number of distinct types and groups. Some items are passive, which add an effect permanently to Isaac, while others only activate when used.

Items dropped in the Binding of Isaac NEVER disappear over time; a coin dropped will remain where it was dropped until you pick it up or leave the floor. A dropped item can be left in its place to be collected at a later time.

Among these types are:

Activated treasures fill your spacebar slot. Only one can be carried at a time. An activated item can be used by pressing space, and unlike a pill or card, activated items recharge over time and can be reused when ready. Each item has a unique effect. Most activated items can only appear once per game with few exceptions, so leaving behind an activated item is typically a permanent choice.

Passives

These treasures, when picked up, add a permanent effect to Isaac. These cannot be removed and are individually counted on the collection screen. Collectible items can be obtained in a variety of ways and most are unique in that, once appearing in game, they will never appear again during that session.

Pills

These go into your Q slot and are one-time-use items. There are a number of different pill styles and effects. At the start of the game, each type is randomly assigned an effect, which remains bound to that pill style for the remainder of the game. Pills start unidentified and are identified once used. Picking up a pill or card while you already have one causes the old one to be dropped.

Cards

Cards are also Q slot items, and are also one-time use. Cards are unidentified when dropped and immediately identified when picked up. Each card has a unique and pre-determined effect. Picking up a pill or card while already carrying one causes the old one to be dropped.

Trinkets

Trinkets fill their own slot and are passive items that affect Isaac in unique ways. Only one can be carried at a time; taking another will replace the current trinket and drop the old one. A trinket collected or left behind will never be randomly generated again during the current game.

Pick Ups

These are common items dropped in game and, when taken automatically confer their effect. This category includes items such as coins, hearts, keys and bombs and disappear once picked up.

There are 198 different collectibles in the game. Below is a list of all of the collectibles, separated into categories. Certain collectibles change the appearance of your character when they are acquired. Collectibles you've found can be seen in the Collection page.

Collectibles

Activated Collectibles

These items are stored in the Spacebar slot and are used up once the button is pressed. The items then recharge in one of two ways. Normally, they charge a number of bars after every room you clear—some items charge one bar at a time, others charge faster. Note that only rooms where the doors close until they are cleared count—Bosses, arenas, enemy rooms, etc. The Collectible Item "Battery" can give bars of charge during combat, on top of the normal recharge. Another Collectible Item, the "9 Volt", will automatically recharge 2 bars when an item is used; this effectively reduces the number of rooms required to charge an item if the item requires 3 or more rooms to charge. In the Wrath of the Lamb DLC, there is another item, the Habit, which will recharge bars when taking damage. To see a clearer version of the in-game arrangement, go to the Collection page.

Note: Any two of the same activated item on the same floor will share charge state, i.e. Finding another of the same activated item when one is not fully charged will not give the player another fully charged version of the item. This can be observed in the Library, which can spawn 2 of the same book.

Item	Icon	Effect	Recharge Time
Anarchist Cookbook		Spawns six troll bombs around the room.	3
The Bean		Causes Isaac to have bad gas, damaging and poisoning any enemy in close vicinity.	1
Bob's Rotten Head		Throws a bomb in the direction Isaac's facing. It does extreme damage, poisons the enemy for 5 seconds, and destroys rocks.	3
The Bible		Transforms Isaac into an angel, allowing him or her to fly over obstacles for the current room only. Instantly kills Mom and Mom's Heart, will kill the player when used on Satan, Isaac or ???.	6
The Book Of Belial		Doubles damage until you exit the room.	3
Book Of Revelations		Adds 1 Soul Heart and makes the next boss a horseman if possible.	6
Book Of Shadows		Grants invulnerability for a short time.	3
The Book Of Sin		Spawns a random Pick Up, Pill or Card.	4
Dead Sea Scrolls		Uses a random Activated Item.	4
Deck of Cards		Gives Isaac a random card.	6
The Dice		Able to reroll Collectibles	3
Doctor's Remote		Sets a big red target on the ground which can be controlled with the arrow keys. After several seconds, a huge explosive missile hits it.	3
Forget Me Now		When activated, the level ends and is freshly regenerated with new rooms, monsters, and items. Disappears after use.	One-time use
The Gamekid		Isaac turns into a Pac-man-like creature, gaining invincibility and the abilit to damage enemies for health. Also causes enemies to flee from you	6
The Hourglass		Slows enemies and enemy projectiles.	2
Kamikaze!		Causes an explosion in the same area as Isaac, causing one heart of damage to yourself.	0
Lemon Mishap		Creates a pool which damages enemies that crosse it	2
Mom's Bottle Of Pills		Upon activation a random pill will spawn in Isaac's inventory, causing the player to drop their current held Q - slot item if any. A player will only receive six different pill types in one playthrough.	6
Mom's Bra		Causes Isaac to wear the bra for a short period of time and freezes enemies for the next 5 seconds.	3
Mom's Pad		Causes enemies to back away from Isaac for a short time.	3
Monster Manuel		Summons a random familiar for the current room only.	4
Monstro's Tooth		Monstro jumps onto a random enemy, doing damage. Cannot be used on a fight against Monstro	3
Mr. Boom		Drops a large bomb.	2
My Little Unicorn		Grants Isaac temporary invincibility while damaging enemies by touch.	6
The Nail		Turns Isaac's body black with twisted horns. Adds one Soul Heart and allows the breaking of rocks by simply walking over them. Increases damage by 1 and decreases speed by 1.	6
The Necronomicon		Damages all enemies in the room significantly.	6
A Pony		While equipped, passively increases speed by 2 and allows Isaac to fly over rocks, pits, blood, and spikes. Upon use Isaac will charge in the direction selected and deals damage to monsters.	4
The Poop		Drops a pile of poop, exactly like the ones that litter the basement.	1
Razor Blade		Deals a certain amount of damage to self, in exchange for increased damage in the current room.	0
The Pinking Shears		Separates Isaac's head and body for a single room. Control is retained for his flying head while his decapitated body will automatically attack enemies in range.	6
Shoop Da Whoop!		Fires a laser from Isaac's mouth.	3
Tammy's Head		Shoots 10 projectiles in a circle around you.	1
Teleport!		Teleports the player to a random room.	2
We Need To Go Deeper!		Creates a trap door to go to the next level.	6
Yum Heart		Restores 1 whole heart.	4

Wrath of the Lamb Activated Collectibles

The following activated items can only be acquired in the Wrath of the Lamb DLC.

Item	Icon	Effect	Recharge Time
Best Friend		Deploys a decoy Isaac that eventually explodes. The explosion can hurt Isaac if they are within the blast radius.	3
Blood Rights		Consumes HP to damage all enemies in the room.	0
The Candle		Throws out a blue flame that can pass over gaps (but not through rocks) that damages anything in its path. Recharges itself.	Recharges itself
Crack The Sky		Calls heavenly beams of light to fall upon your enemies dealing mass damage to whatever they hit.	4
Crystal Ball		Reveals the map and gives a random card or soul heart.	6
D20		Randomly changes all Pickups in the room.	6
Dad's Key		Unlocks all normal doors in room when used. Allows the player to exit a fight.	2
Guppy's Head		Spawns 2-4 Blue Flies to damage enemies.	1
Guppy's Paw		Removes one Heart Container in exchange for gaining 3 Soul Hearts.	0
IV Bag		Exchanges hearts for coins.	0
Notched Axe		Breaks a single rock when activated.	1
Prayer Card		Grants half an Eternal Heart per use.	6
Portable Slot		Same effect as the Slot Machine.	0
Remote Detonator		Bombs you place explode only when you use this item. Gives 5 bombs.	0
Spider Butt		Damages all enemies in the room and inflicts slowdown condition like Spider's Bite.	2
Telepathy For Dummies		Tears track targets for one room.	2
White Pony		Increases speed by 2 and allows Isaac to fly while equipped. Upon use Isaac will charge in the direction selected and deals damage to monsters. In addition, when used it also has the Crack the Sky effect.	6

Passive Collectibles

These items generally give you some kind of a boost to your stats, or add a special passive ability. They take effect immediately once picked up, and continue for the rest of the game (except for several items that do not provide any lasting effect).

Edmund McMillen split them up in his blog into the subcategories weapon item, stat padding items, passive items, and familiars.

Item	Icon	Effect
<3		Increases available heart containers by 1 and restores all health.
1UP		Gives an extra life. Upon death, you will respawn in the previous room with full health and lose the 1UP.
9 Volt		Leaves Isaac with two bars already charged after using an item. Upon pickup, Isaac's current activated item will be fully charged.
The Battery		Gives Isaac an extra charge every few seconds per room, up to a maximum of 3 charges.
The Belt		Increases Speed by 2.
Blood Bag		Increases HP by 1, Speed by 1 and restores 4 hearts. More than one can be obtained during a same playthrough
Blood Of The Martyr		Increases Damage by 2, turns Isaac's tears into blood tears.
Bobby-Bomb		Gives 5 bombs and causes all bombs to slowly slide towards the closest enemy.
Bomb Bag		Isaac is followed by a small bag that drops a Bomb, 1+1 Free, or a Troll Bomb every 3 rooms.
Boom!		Gives 10 bombs.
Breakfast		Increases HP by 1.
Brimstone		Changes tears to a chargable laser that pierces all objects in its path It can only be fired after a short charge-up period
Brother Bobby		Follows Isaac around shooting normal tears.
Bucket Of Lard		Gives two empty heart containers, heals by half a heart but decreases speed by 1.
Charm Of The Vampire		Killing 13 monsters heals the player for half a heart.
Chocolate Milk		Allows Isaac to charge shots making them a lot stronger and larger, and turns them brown. Tears will no longer automatically fire while holding down arrow keys.
The Common Cold		Gives Isaac's shot a chance of poisoning enemies for a few seconds and turns tears green.
The Compass		Shows the icons of special rooms (Item room, Boss room, the Shop, the Arcade, Mini-boss room) on the map without revealing rooms.
Cube Of Meat		The first pick up gives a floating cube similar to a Pretty Fly that damages enemies. The second pick up changes it into a floating head that shoots red tears. The third pick up changes it into a humanoid Meat Boy, who walks around chasing enemies, but no longer shoot projectiles. (This form pushes bombs around, it does this to spite you) The fourth pick up increases his size and damage. A fifth pick up will create another cube of meat orbital which then advances to another Super Meat Boy. → →→
Cupid's Arrow		Gives Isaac piercing shots that will travel through enemies.
Dead Bird		Whenever Isaac takes damage, the bird starts attacking nearby enemies while flying over obstacles. The effect only lasts for the current room.
Dead Cat		Your HP is set to 1. You are followed by a floating cat head and have 9 lives (these still count as deaths on the statistics screen). You can increase your max HP as normal, but after each death it will reset to 1 again.
Dessert		Increases available heart containers by 1.
Dinner		Increases available heart containers by 1.
Distant Admiration		A red attack fly circles further out than the Halo of Flies/Pretty Flies, but closer than Forever Alone. The attack fly can deal damage to all enemies, unlike the other flies which can only block shots and hurt enemy flies. Deals more damage than Pretty Fly / Forever Alone.
Demon Baby		Follows Isaac and automatically fires at enemies in its reach.
A Dollar		Sets your penny counter to 99.
Dr. Fetus		Replaces Isaac's shot with a bomb. Only one bomb can be shot at a time, and it will slide a fixed range before exploding.
Forever Alone		Spawns a blue attack fly that orbits a long distance from Isaac.
Guardian Angel		Spawns a guardian angel that orbits Isaac. Does damage on touch, blocks bullets and doubles the speed of other orbiting items.
Growth Hormones		Increase Speed and Damage by 2 each.
The Halo		Increases all stats except range by one.
Halo Of Flies		Grants 2 Flies that circle Isaac. Blocks bullets and damages fly enemies on touch.
The Inner Eye		Gives Isaac a triple shot, sets Tears to minimum
The Ladder		Allows Isaac to walk across gaps one square across by automatically placing a ladder between the two walkables.
Little C.H.A.D.		Isaac is followed by Little C.H.A.D, who will drop a half Heart every 2 rooms.
Little Chubby		Adds a small grub that follows Isaac. Charges forward and deals touch damage to any enemies in his path. Will attack when the player attacks with a moderate cooldown time before he can attack again.
Little Gish		Follows Isaac around shooting tar projectiles that reduce enemies' movement speed, shot speed, and range for a few seconds.
Little Steve		Follows Isaac around shooting homing projectiles
Loki's Horns		Gives a random chance for projectiles to fire in a cross (+) pattern.
Lord Of The Pit		Isaac can fly over all obstacles, including damage floors, spikes, rocks, and pits.
Lucky Foot		All pills picked up will have positive effects (same effect as the PhD but without pill identification). Increases the chance of getting items from piles of poo and fires. Increases the chance of winning the Skull Challenge in the Arcade room from 33% to 50%. Increases the chances of getting items from gold chests.
Lunch		Increases available heart containers by 1.
A Lump Of Coal		Increases damage based on how far tears have traveled (tear size increases as it gets further away).
Magic Mushroom		Fully heals Isaac, increases all their stats by 1 and increases tear size.
Magneto		Pulls Pick Ups towards Isaac.
The Mark		Increases Damage by 2 and adds one soul heart.
Max's Head		Increases damage by 1, increases the size of tears and causes tears to inflict more knockback on enemies.
Mini Mushroom		Increases speed and range by 1. Shrinks Isaac's hitbox, making dodges easier.
Mom's Contacts		Gives Isaac a petrifying shot that will randomly freeze enemies solid for a few seconds.
Mom's Eye		Increases Tears stat and gives Isaac an eye on the back of his head, allowing you to shoot in both directions at the same time.
Mom's Heels		Increases Range by 2.
Mom's Knife		Once collected, Isaac no longer shoots tears, he shoots a knife in boomerang style. The range of throw increases by charging the shot. Can also be used as a melee weapon while not fired.
Mom's Lipstick		Increases Range by 1.
Mom's Underwear		Increases Range by 1.
Money = Power		Increases damage based on the number of coins the player has at the moment.
Mr. Mega		Gives Isaac 5 bombs, and makes all dropped bombs large bombsIncreases the damage of bomb.
My Reflection		Gives Isaac's tears a boomerang effect and range is set to default range.
Number One		Sets Isaac's tears to their maximum rate of fire and minimum range.
Odd Mushroom (Thin)		Increases speed by 1, increases Tears to maximum while reducing projectile damage by 1.
Odd Mushroom (Large)		Increases damage by 1, and increases maximum hearts by 1 while reducing speed.
Ouija Board		Allows Isaac's shots to go through rocks or obstacles.
The Pact		Increases Damage by 1 and rate of fire by 2. The player also gains 2 soul hearts.
The Parasite		Makes the Isaac's tears split in two when they hit something.
Pentagram		Increases Damage by 2.
PHD		Changes negtive Pill effects into positive ones. Also causes Blood Banks to drop more money
A Quarter		Gives you 25 pennies.
Raw Liver		Increases available heart containers by 2 and completely restores health. Reduces range by 1.
The Relic		Isaac is followed by a small blue cross that will drop a Soul Heart every 4 rooms.
Robo-Baby		Follows Isaac around, shooting enemies with an eye laser similar to Technology.
Roid Rage		Increases Speed and Range significantly.
Rosary		Increases Faith by adding 3 Soul Hearts and increases the chance for The Bible to appear in the subsequent levels of the playthrough.
Rotten Meat		Increases available heart containers by 1.
Sack Of Pennies		Isaac is followed by a small bag that drops a coin every 2 rooms. Usually a penny, sometimes a nickel.
The Sad Onion		Doubles the Tears Stat
Sister Maggy		Follows Isaac around shooting blood tears.
Skatole		All the various fly type enemies no longer harm you, shoot, or split.
Skeleton Key		Sets your key count to the maximum of 99.
Small Rock		Increases damage by 2, increases tears by 1, decreases speed by 1.
Spelunker Hat		Reveals the Secret Room and Top Secret Room when passing by it and reveals if a room contains a mini-boss.
Spider's Bite		Gives Isaac's shots a chance of slowing enemies for a few seconds.
Spoon Bender		Gives Isaac's shots the ability to curve towards enemies.
Steam Sale		Reduces all Shop prices by 50%, rounded down.
Steven		Increases Damage by 2.
Super Bandage		Increases HP by 1 and gives 2 soul hearts.
Technology		Gives Isaac a laser shot with unlimited range. Shots pierce enemies but not rocks, fire, or poop. Shots can't be angled, and will not provide knockback.
Transcendence		Removes Isaac's body, allowing flight over obstacles, spikes and pits.
Treasure Map		Reveals all rooms for every floor, including the Secret Room. However, it does not reveal icons.
The Virus		Gives Isaac the ability to poison enemies he touchs for a few seconds.
The Wafer		Reduces all damage received by half, rounding up to the nearest half-heart.
Whore Of Babylon		If Isaac has only half a heart damage is increased by 3 and speed by 2.
Wiggle Worm		Gives Isaac waving shots and increases attack speed by 1.
Wire Coat Hanger		Increases Tears by 2.
Wooden Spoon		Increases speed by 2.
XRay Vision		Reveals and opens Secret room entrances.

Wrath of the Lamb Passive Collectibles

The following collectible items can only be acquired if you have the Wrath of the Lamb DLC.

Item	Icon	Effect
3 Dollar Bill		Effect given changes every room.
Abel		Mirrors Isaac's movements. Shoots in opposite direction to the player.
Ankh		When killed, respawns in the previous room as ???, regardless of the fact he is unlocked or not. After respawn, all future HP upgrades will be soul hearts only. Only works once.
The Black Bean		When taking damage, Isaac farts, causing poison damage to all enemies in range.
Bloody Lust		Increases damage each time Isaac kills an enemy for the current room.
Bob's Curse		Gives 5 bombs and grants all bombs poison effect.
Box		Spawns 1 of each item: 1 coin, 1 key, 1 bomb, 1 heart, 1 card, 1 pill, 1 trinket.
Bum Friend		A portable beggar who will follow you, pick up coins for himself, and occasionally drop Pick Ups. Does not spawn Collectibles. The beggar pushes bombs around, he does this to spite you
Cat-O-Nine-Tails		Tears will travel faster.
Celtic Cross		Small chance to cast the a protecting shield on Isaac upon taking damage.
Chemical Peel		Tears fired from left eye do increased damage.
Daddy's Love		Daddy Long Legs' shadow follows player and stamps on enemies.
Dead Dove		Gives Isaac spectral tears and flight.
Epic Fetus		Tears become guided missiles (See Doctor's Remote).
Fate		Isaac gains flight and an Eternal Heart.
Ghost Baby		Familiar that shoots spectral tears.
Guppy's Hair Ball		Loosely follows behind Isaac. Can be swung like a flail by rapidly spinning Isaac in a circle. Grows bigger by killing enemies
Guppy's Tail		Increases chance of gold chests and normal chests.
Habit		When hit, refills some item charge.
Harlequin Baby		Familiar that shoots a pair of tears diagonally every second while Isaac is firing.
Holy Grail		Adds 1 empty heart container and gives flying ability.
Holy Water		When Isaac receives damage the vial breaks and a blue spot that damages foes forms, similar to that of Lemon Mishap. The vial is reformed upon entering a different room.
Infestation		1-3 Blue Flies randomly spawn every time Isaac gets hit.
Ipecac		Green projectiles fired from the mouth causing poison/explosive damage.
Jesus Juice		Increases Range and Tears by 1
Magic 8 Ball		Increases Shot Speed. Drops a Tarot Card when picked up.
MEAT!		+1 Max HP and tears.
Mitre		Greatly increases the chance of replacing spawned hearts with soul hearts.
Mom's Purse		Hold 1 additional trinket.
Mom's Coin Purse		Spawns several pills around Isaac.
The Mulligan		Chance to spawn Blue Flies on successful hits, which charge current target.
Mutant Spider		Shoot four tears at once, greatly reduces tear firing rate.
Pageant Boy		Spawns several coins around Isaac.
The Peeper		Gives Isaac a familiar eye that floats around the room, damaging enemies on contact Tears fired from left eye become red (cosmetical only)
Polyphemus		Makes Isaac shoot one huge tear, also reduces Tears to minimum. If tear does more damage than an enemy's life, the tear continues to travel with the extra remaining damage.
Pyro		Adds 99 Bombs.
Rainbow Baby		Tear Effect changes every shot.
Sacred Heart		Shots are larger, travel slower and home in on enemies. Damage is multiplied. Decreases Tears by 1. Gives 1 Soul Heart and restores full Health on Pick up.
Sacrificial Dagger		Dagger orbits Isaac, very high damage.
Scapular		Whenever Isaac is downed to 1/2 of his last Heart, Aura around his head temporarily vanishes and he is granted 1 Soul Heart.
SMB Super Fan!		Increases all stats except Speed by 1. Reduces Speed by 1.
Speed Ball		Increases movement speed and causes tears to travel faster.
Spirit Of The Night		Grants Isaac flight and spectral tears.
Squeezy		+1 tears and spawns 2 soul hearts.
Stem Cells		+1 heart container. It also heals a half heart.
Stigmata		Boosts Isaac's damage by 1 and grants you one heart container.
Technology 2		Fires a continuous laser as you shoot tears. Pierces enemies.
Toothpicks		Increases Tears. Range goes down by 1 and causes tears to travel faster.
Tough Love		Isaac randomly shoots teeth instead of tears, dealing more than triple damage, the extra damage can go over the damage limit allowing you to deal triple the max damage.

Start a Discussion Discussions about Items

IMMORTAL COMBO

8 messages
- Meatninja
  
  92.237.180.198 wrote:The TRUE immortal combo is brimstone and That cyclops...thing Got it? Why would it make you immortal? It's just v... 2013-05-24T16:39:06Z
epic fetus

15 messages
- Doomspeaker
  
  Oil Rope Bombs is 100% on spot. BoI has lots of misleading texts. 2013-05-17T12:43:08Z
- A Wikia contributor
  
  Being buggy, I usually just close the game and open it up after. It gives me the steam achievement, and confirm me that I can have the item. H... 2013-05-19T04:31:59Z

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Items

Contents

Activated Items