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Items are an integral part of gameplay from Rebirth. They modify a character's stats, grant or modify abilities, and many other things. Generally RNGesus will deal you a bad set of items like "Soy Milk"
Items in general are classified into a number of distinct types and groups. Some items are passive, which add an effect permanently to Isaac, while others only activate when used.
This category has the following 3 subcategories, out of 3 total.
Pages in category "Items"
The following 161 pages are in this category, out of 361 total.