Ad blocker interference detected!
Wikia is a free-to-use site that makes money from advertising. We have a modified experience for viewers using ad blockers
Wikia is not accessible if you’ve made further modifications. Remove the custom ad blocker rule(s) and the page will load as expected.
Isaac is a titular character and named after one of the Biblical people. Isaac may refer to:
Bosses / Characters
- Isaac's Tears - One of the activated items in Rebirth.
- Isaac's Heart - One of the passive items in Rebirth.
- Isaac's Fork - A trinket.
- Isaac's Last Will - A game over screen that displayed after getting killed.