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IsaacHDIsaac Rebirth

In-game sprite from the original game
Half heart
The Caves
The Depths
The Womb
Related Monster(s)
Red Host
Walking Host
Walking Red Host

Hosts are monsters appearing in both The Binding of Isaac and the Rebirth remake. They're immobile skulls that reveal a fleshy stem when they rise up. They are commonly found in The Caves, and less commonly in The Depths, The Womb, and Sheol.



Host smirking.

Hosts stay immobile at a single spot, unable to be damaged. They only rise up for a short amount of time when Isaac gets in front of them. After rising up, they fire 3 blood shots with considerable range and then fall down again. You can however, move the hosts via your tears, though it takes a rather long time and is tedious. 

Hosts only take damage when they rise up. Attacking them when they are lowered down will prevent them from rising up again for a short period of time.

There are only few ways to damage a Host in its invulnerable form; Knocking it into Spikes (kills them instantly), activating and using Dead Bird, or shooting them with ethereal tears. Using Bombs and high damage attacks (Such as Brimstone) on a lowered host only causes the skull to wrinkle and smirk at you. Tear effects such as Poison do trigger while it is invulnerable, but will not damage them unless they rise up.

They only rise up when they have orthogonal line-of-sight on the player. Therefore, staying diagonal to them or behind obstacles can be used as a tactic to avoid getting shot. Furthermore, if the player remains on that orthogonal vector, the host will not rise back up until the player approaches along a different vector. For example, moving to a host's left side will make it rise up and shoot; if the player still stays on the left, the host will not move, sometimes even after moving to a diagonal safe zone. It's only once the player moves to the host's up or down line-of-sight direction that it will rise up again.


  • In Rebirth, from The Depths and Necropolis chapters, they can be spawned after exploding the skulls with bombs.
    • They also can be spawned after killing the Meatball enemy from the Afterbirth expansion.


  • Hosts are from another game made by Edmund McMillen, called Host.
  • The Hosts' skulls are used in the Shell Game.
Normal monsters
I Blob-button

I. Blob
More monsters coming soon...
Flies Black FlyAttack FlyMoterEternal FlyPooterFat FlyBoom FlyRed Boom FlyDrowned Boom FlySuckerSpitDart FlySwarm FlyRing FlyLevel 2 FlyFull FlyHush FlyBall of Flies
Spiders SpiderBig SpiderTriteRaglingRag TriteLevel 2 SpiderTicking SpiderBaby Long LegsCrazy Long LegsWall CreepBlind CreepRage Creep
Spheres BoilGutSackBlue BoilWalking Variants
Mulligans MulliganMulligoonMulliboomHiveSwarmerNestDrowned Hive
Headless HopperFlaming HopperLeaperPacerGusherSplasher
Gapers GaperFrowning GaperGurgleMr. MawFlaming GaperCyclopiaSkinnyRottyNullGreed GaperBlue GaperSwinger
Heads HorfPsychic HorfMawRed MawPsychic Maw
Globins GlobinGazing GlobinBlack GlobinDank Globin
Knights KnightSelfless KnightFloating KnightBone Knight
Blobs ClottyClotMega Clotty
Maggots MaggotChargerSpittyConjoined SpittyDrowned ChargerGrub
Body parts Mask + HeartBrainMemBrainGutsMama GutsEyeBloodshot EyeMom's HandDead Mom's HandScarred GutsNerve EndingStone Eye
Worms Para-BiteCod WormScarred Para-BiteRound WormNightcrawlerRoundyUlcer
Leeches LeechKamikaze LeechHoly Leech
Poop DipCorn DipSquirtDank SquirtDinga
Skeletons BonyBlack BonyDeath's HeadDank Death's HeadFlesh Death's Head
Ghosts Lil' HauntWizoobRed Ghost
Bats One ToothFat Bat
Fatties FattyFlaming FattyConjoined FattyBlue Conjoined FattyPale Fatty
Hosts HostRed HostWalking HostWalking Red Host
Vises VisDouble VisChubberCage VisScarred Double Vis
Tumors TumorPsy TumorCamillo Jr.
Spikes Wall HuggerSlidePoky
Babies BabyAngelic BabyEmbryoImp
Homunculuses HomunculusBegotten
Keepers KeeperHanger
Grimaces Stone GrimaceVomit GrimaceGaping MawTurret GrimaceBrimstone Grimace
Oobs OobBlack Maw
Others FredLumpB. LickerDukieDopleEvil TwinMeatball

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