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Xxx form2 Isaac Rebirth

Guppy's Head is an activated item first added to the Wrath of the Lamb DLC for the original game, and also appear in the Rebirth remake. It is Guppy's decapitated head.

Effects[]

  • Upon activation, 2-4 Blue Flies are spawned.

Synergies[]

Guppys Head Icon

Guppy's Head from the original game.

Trivia[]

  • The item's icon from the original game is surrounded with flies.

Bugs[]

  • From the original game, when entering a door while/right after using Guppy's Head, the flies will not spawn.

Related Achievements[]

Guppys Hairball
"Guppy's Hairball" - Collect three Guppy-related items in a single playthrough.

Items
Passive Items Tear Modifiers: The Inner EyeSpoon BenderMy ReflectionSkatoleCube of MeatCupid's ArrowDr. FetusMom's EyeWiggle WormTechnologyChocolate MilkLoki's HornsLittle ChubbySpider's BiteThe Common ColdThe ParasiteMom's ContactsMom's KnifeOuija BoardBrimstoneA Lump of Coal

(Wrath of the Lamb DLC: IPECACTough LoveTechnology 2Mutant SpiderEpic FetusPolyphemusSacred Heart)

Stat Ups: The Sad OnionMax's HeadNumber OneBlood of the MartyrMagic MushroomRoid RageRaw LiverLunchDinnerDessertBreakfastRotten MeatWooden SpoonThe BeltMom's UnderwearMom's HeelsMom's LipstickWire Coat HangerStevenPentagramThe MarkGrowth HormonesMini MushroomThe PactSmall RockSuper BandageRobo-BabyLittle C.H.A.D.Little GishLittle SteveThe RelicThe HaloMoney Equals PowerBlood BagOdd Mushroom (Thin)Odd Mushroom (Large)Whore Of BabylonBucket Of Lard
(Wrath of the Lamb DLC: StigmataSpeed BallChemical PeelBloody LustCat-O-Nine-TailsStem CellsTooth PicksSMB Super Fan!MEAT!Magic 8 BallSqueezyJesus Juice)

Familiars and Orbitals: Brother BobbyHalo Of FliesDistant AdmirationSister MaggyGuardian AngelDemon BabyDead BirdForever AloneSack Of PenniesBomb Bag
(Wrath of the Lamb DLC: Bum FriendThe PeeperGhost BabyHarlequin BabyDaddy LonglegsSacrificial DaggerRainbow BabyHoly WaterGuppy's Hair BallAbel)

Others: 1UPThe VirusLess Than ThreeSkeleton KeyA DollarA QuarterBoom!TranscendenceThe CompassPHDRosaryXRay VisionLucky FootMagnetoTreasure MapThe LadderCharm Of The VampireThe BatterySteam SaleDead CatLord Of The PitSpelunker HatMr. MegaThe Wafer9 VoltBobby-Bomb
(Wrath of the Lamb DLC: Guppy's TailMom's PurseBob's CursePageant BoyScapularInfestationThe MulliganHabitSpirit Of The NightAnkhCeltic CrossMitreFateThe Black BeanHoly GrailDead DovePyro3 Dollar BillMom's Coin PurseBox)

Activated Items Base Items: The PoopMr. BoomTammy's HeadMom's BraKamikazeMom's PadBob's Rotten HeadTeleport!My Little UnicornYum HeartDoctor's RemoteShoop Da Whoop!Lemon MishapThe HourglassThe NailWe Need To Go Deeper!Deck of CardsMonstro's ToothThe GamekidMom's Bottle of PillsThe DiceThe Pinking ShearsThe BeanDead Sea ScrollsRazor BladeForget Me NowA Pony

(Wrath of the Lamb DLC: Guppy's PawIV BagBest FriendRemote DetonatorGuppy's HeadPrayer CardNotched AxeCrystal BallCrack The SkyThe CandleD20Spider ButtDad's KeyPortable SlotWhite PonyBlood Rights)

Books: The BibleThe Book of BelialThe NecronomiconBook Of RevelationsBook of ShadowsAnarchist CookbookThe Book Of SinMonster Manuel
(Wrath of the Lamb DLC: Telepathy for Dummies)

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