Gapers will attempt to rush at the player by taking the most direct route possible. If there is no way to reach the player, they will not move until a path exists. Since Gapers can block the paths of other Gapers, however, they have a tendency to go in unexpected directions. They are not difficult to kill and do not take much damage before dying. On occasion, they can turn into Pacers or Gushers before dying. Gapers resemble Isaac, but have blood in place of the tears running down Isaac's face. Gapers are found in Basement and Cellar.
They shoot IPECAC shots at the player at very short range, which deal one heart of damage to the player in a considerable area. These shots will kill other enemies in thier Area of Effect, but Gurgles themselves are immune to their own IPECAC shots. Like other enemies' explosive projectiles, Gurgles' shots can be used to shatter Rocks or open Secret Rooms by making Gurgles fire at the appropriate area.
Gurgles are somewhat more predictable and accurate in their shots compared to guts and walking guts, because they will always shoot at the player's position. However, the timing of their shots is unpredictable. As such, an effective strategy of delivering explosives to a particular area (e.g. Tinted Rock or potential secret room entrance) is to stand still in that position as long as possible before moving to avoid getting touched, in order to prompt the Gurgles to shoot their projectiles at you.
Gurgles are most commonly found in groups; they also move quite a bit slower than regular Gapers.