Wikia

Monsters are the many creatures encountered throughout the game.

Most monsters (with a few exceptions) will damage the player by either touching them or shooting them with bloody tears. It is usually advised to backpedal from a distance to best avoid being damaged. Along with the normal varieties of monsters, Champion versions of monsters can be found lurking about. These monsters are often like normal monsters, but have a color tint or size change and drop basic Pickups (or rarely, a Chest) upon death. There are also Champion version of Bosses.

Monster List Edit

Monster	WotL DLC
Black Fly
Attack Fly
Moter
Eternal Fly	✔
Pooter
Fat Fly	✔
Boom Fly
Red Boom Fly
Sucker
Spit	✔
Spider	✔
Big Spider	✔
Trite	✔
Boil
Gut	✔
Sack	✔
Walking Boil	✔
Walking Gut	✔
Walking Sack	✔
Mulligan
Mulligoon
Mulliboom	✔
Hive
Swarmer	✔
Hopper
Flaming Hopper
Leaper
Pacer
Gusher
Gaper
Frowning Gaper
Gurgle	✔
Mr. Maw
Horf
Maw
Red Maw
Psychic Maw	✔
Globin
Gazing Globin
Knight
Selfless Knight
Mask + Heart	✔
Clotty
Clot
I. Blob	✔
Maggot
Charger
Spity
Brain
MemBrain
Guts
Mama Guts	✔
Buttlicker	✔
Para-Bite
Fred
Lump
Leech
Kamikaze Leech
Holy Leech	✔
Host
Red Host
Vis
Double Vis	✔
Chubber	✔
Poky
Slide	✔
Eye
Bloodshot Eye
Dople
Evil Twin
Embryo
Baby
Angelic Baby	✔
Keeper	✔
Hanger	✔
Stone Grimace
Vomit Grimace	✔

Monster List by Floor Edit

The Basement
Pooter Fly Gaper Horf Gusher Hopper Mulligan Mulligoon Clotty Clot I.Blob (very rare) Spider Moter Sucker Embryo

Cellar
I.Blob (very rare) Clot Sack Gaper Mulligan Mulliboom Spider Big Spider Trite

The Caves
I.Blob (very rare) Boom Fly Charger Clot Clotty Fly Gusher Hopper Host Hive Maw Maggot Moter Spider Spitty Sucker Embryo Knight Selfless Knight (Rare) Leaper (Rare) Mr. Maw (Uncommon) Bosses up to the Caves

Catacombs
Keeper I.Blob (very rare) Buttlicker Embryo Mulliboom Psychic Maw Spider Embryo Fat Fly Trite Gurgle Walking Boil Walking Gut Walking Sack

The Depths
Baby Boil Boom Fly Brain Globin Guts Hive Host Knight Selfless Knight (rare) Leaper Leech Embryo Kamikaze Leech (rare) Mr. Maw Moter MemBrain (very rare) Pooter Psychic Maw Spiders Vis Bosses up to the Caves

Necropolis
Angelic Baby (Uncommon) Keeper Mama Guts I.Blob (very rare) Boom Fly Buttlicker Hanger Mask + Heart Mulliboom (rare) Spider Slide Swarmer Embryo Vis Double Vis Gurgle Walking Boil Walking Gut Walking Sack

The Womb
I.Blob (very rare) Brain Dople Eye Eye Fly Fred Leech Holy Leech (uncommon) Host Lump Embryo Membrain Para-Bite Poky Globin Guts Mr. Maw (uncommon) Spider Vis Bosses up to the caves

Utero
Angelic Baby (uncommon) Mama Guts Buttlicker Dople Fred Guts Gurdy Jr. Mask + Heart Heart Para-Bite Spiders

Sheol
I.Blob (unconfirmed) Leech (rare) Kamikaze Leech Holy Leech (uncommon) Headless Horseman's Head Selfless Knight Evil Twin Sucker Spit Globin (rarely) Spider (unconfirmed)
Two Greeds and a whole Fistula.
All bosses up to the Depths as well as Death, The Fallen, and the Headless Horseman.
Some bosses will appear in pairs of themselves, such as Gemini.
Gurdy will not appear.
*Rarely monsters from early levels, such as a non-aggressive fly will spawn in rooms by themselves. This might be a bug.

Cathedral
Angelic Baby I.Blob Clot Holy Leech Spit Spider (unconfirmed)

Monster replacementsEdit

Some monsters in the Binding of Isaac are randomly replaced by similar counterparts. These can either be "champion" versions that are recolored or completely different enemies with modified attacks.

Champion EnemiesEdit

Normal enemies can be recolored to become champion enemies, which by default have twice as much HP as their normal counterparts. Similarly, some champion enemies are able to deal full heart damage regardless of the level. Champion enemies will always drop a free pickup when killed.

Enemy VariantsEdit

These variants may replace normal enemies in a room

Some variants will additionally count as champion enemies if encountered on certain floors. For example, Bloodshot Eyes, Selfless Knights, Kamikaze/Holy Leeches and the Evil Twin can be considered champions when encountered in the Womb or earlier and will drop a pickup when killed.

Replacement/Variation Chart
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