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Delirious is an activated item added to the Afterbirth † DLC.
Delirious (Aslo known as Lil' Delirium) is a familiar that can shape-shift, just like his bigger version. However, he transforms into any familiar, making him a Swiss-army goop, if you will. This is extraordinarily useful, as you can get (for a little while) Lil' Brimstone, Little Chubby, Dry Baby, and so on.