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IsaacHDIsaac Rebirth

Clot is a oil-type of the normal Clotty appearing in both The Binding of Isaac and the Rebirth remake.


Clot is a fairly uncommon enemy found in The Basement, The Caves and The Depths. In Wrath of the Lamb, Clots also uncommonly appear in Cellar, Catacombs and Utero but are more common in Cathedral.

Clots flit about the room haphazardly, firing black projectiles in diagonal directions at random intervals. It is much easier to defeat than Clotty, since you will be perfectly safe if you shoot at it while standing directly in front or to the side of it. It is only truly dangerous when there are other enemies in the room.


  • The Clot resembles a black blob with yellow eyes and white teeth, and is almost identical to the protagonist Gish, from the game of the same name, which was also created by Edmund McMillen.
  • In the credits, the picture of the Clot looks like the top half of a Clotty, indicating a possible change in the design of the Clot during the game's development.


  • When a Clot is in the room, using bombs or defeating other enemies will leave the same black goo marks as Clots. Ranged enemies will also shoot the same black projectiles as the Clots.
Normal monsters
I Blob-button

I. Blob
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Flies Black FlyAttack FlyMoterEternal FlyPooterFat FlyBoom FlyRed Boom FlyDrowned Boom FlySuckerSpitDart FlySwarm FlyRing FlyLevel 2 FlyFull FlyHush FlyBall of Flies
Spiders SpiderBig SpiderTriteRaglingRag TriteLevel 2 SpiderTicking SpiderBaby Long LegsCrazy Long LegsWall CreepBlind CreepRage Creep
Spheres BoilGutSackBlue BoilWalking Variants
Mulligans MulliganMulligoonMulliboomHiveSwarmerNestDrowned Hive
Headless HopperFlaming HopperLeaperPacerGusherSplasher
Gapers GaperFrowning GaperGurgleMr. MawFlaming GaperCyclopiaSkinnyRottyNullGreed GaperBlue GaperSwinger
Heads HorfPsychic HorfMawRed MawPsychic Maw
Globins GlobinGazing GlobinBlack GlobinDank Globin
Knights KnightSelfless KnightFloating KnightBone Knight
Blobs ClottyClotMega Clotty
Maggots MaggotChargerSpittyConjoined SpittyDrowned ChargerGrub
Body parts Mask + HeartBrainMemBrainGutsMama GutsEyeBloodshot EyeMom's HandDead Mom's HandScarred GutsNerve EndingStone Eye
Worms Para-BiteCod WormScarred Para-BiteRound WormNightcrawlerRoundyUlcer
Leeches LeechKamikaze LeechHoly Leech
Poop DipCorn DipBrown DipSquirtDank SquirtDinga
Skeletons BonyBlack BonyDeath's HeadDank Death's HeadFlesh Death's Head
Ghosts Lil' HauntWizoobRed Ghost
Bats One ToothFat Bat
Fatties FattyFlaming FattyConjoined FattyBlue Conjoined FattyPale Fatty
Hosts HostRed HostWalking HostWalking Red Host
Vises VisDouble VisChubberCage VisScarred Double Vis
Tumors TumorPsy TumorCamillo Jr.
Spikes Wall HuggerSlidePoky
Babies BabyAngelic BabyEmbryoImp
Homunculuses HomunculusBegotten
Keepers KeeperHanger
Grimaces Stone GrimaceVomit GrimaceGaping MawTurret GrimaceBrimstone Grimace
Oobs OobBlack Maw
Others FredLumpB. LickerDukieDopleEvil TwinMeatball

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