The Binding of Isaac Wiki

Box of Friends

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Keeper sprite Celtic Cross Rebirth

Box of Friends is an unlockable activated item. Lilith starts with this item, but she must defeat Ultra Greed to unlock it.


  • Duplicates your current Familiars for the duration of the current room.
  • If Isaac has no familiars, a Demon Baby will spawn for the duration of the room.


Related Achievements

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