D666

"Reroll Evil"

Like the D6 but rerolls the item into a devil item. If there is no pedestal in the room then it randomly rerolls one of Isaac's items into a devil room item(excluding space bar items). If the devil pool has been depleted, the item will disappear and give isaac a 2x damage multiplier.

Pool: Devil (obviously)

Unlock: Use every single dice item.

Broken Cap

"No Limits!"

Takes away all stat increase limits

Pool: Shop, Secret room

Unlock: Use a Blank card with a Jera on a battery in the chest

The Divine Reward

"Trademarked by God!"

Maxes out all stats

Pool: Angel

Unlock: Defeat the Lamb and Mega Satan without taking damage

D2

"Reroll Toys"

6 room recharge, rerolls trinkets.

Pool: Shop, Treasure

Unlock: Use the smelter 5 times on one run

D777

"Divine Reroll'

10 room recharge, like D6 but rerolls items in angel room items, can only be used once per floor.

Pool: Angel

Unlock: Use the D6 on angel room 5 times

D9

"Reroll Stuff"

6 room recharge, rerolls pills, cards, and runes.

Pool:Treasure

Unlock: Use every card, pill, and rune there is.

Tech Negative

"It's a bit glitchy"

Like technology, but instead of piercing the laser will arc from enemy to enemy, similar to Jacob's ladder

Pool: Super Secret Room, Shop

Unlock: Have 3 tech items on one run.

D-

"R̴̢̢̳̞͎̺̤̙̲͕̠̹̘͛͛e̶̢̡̛͉͔̤̞̹̰̺͇̟͎̦̠͓̎̈́͐͆̉̉͆̌̽̅̚r̷̡̧̩̤̹̲̖̣̤̞͍̭̜̫͈͊̈͐́ó̷̮͔̫̗̈́͊̅̽́̇̆͋͑̕͘͝ļ̵̝͕̾̍̓̈́̑̕͜l̸͚̬̳͖̯̫̩̯̾̅̊̀̂̊̽"

Basically the D100, but item pools never run out

Pool: Anywhere, very rare

Unlock: Use the D100 10 times

Trinket: Broken laser pointer

Gives you a small chance to have a random tech effect in a room.

Unlock: Same as Tech Negative

Virus

"Teletears"

Isaac now has a small chance to shoot out a tear that will teleport an enemy to a random location.

Pool: Anywhere, but rare.

Unlock: Find I AM ERROR room 5 times