They look nearly identical to regular eyes - except, despite their names, are grey-colored with black-pupils and lack of veins.
If encounted in The womb, it will be counted as a champion, and will drop a Pick Up upon death. Instead of firing a Technology laser at Isaac, they will instead fire a Brimstone laser. This laser hits much more often, thus making it much more dangerous, especially in groups.
- The Brimstone lasers fired by Bloodshot Eyes usually do not reach the end of the room, and thus appear to be cut. This is only a graphical glitch, and Isaac can still be hurt by the lasers even if they don't reach him.