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Black Fly

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For other uses, see Fly (disambiguation).
For the monster from The Legend of Bum-bo, see Fly.

IsaacHDIsaac RebirthKeeper sprite

Black Flies (also known as Flies for short) are one of the most common enemies, found in almost all floors from both The Binding of Isaac and the Rebirth remake. They can naturally spawn in The Basement. They also come in sort of multiple variants.



Black Fly from the original game.

Black Flies buzz around the room randomly, making buzzing noises, often moving away from the player. They cannot damage Isaac at all, even by touch, making them completely harmless. However, they can turn into relatively dangerous Pooters if they fly around the Poop for too long or come in contact with a golden poop.



  • During the credits from the original game, the Black Fly, Psychic Maw, and Blastocyst's images are the only ones that are animated.
  • Black Flies, along with other type of flies, are one of the enemies with lack of champion variants.
    • Same apply to Spiders and few other monsters.
  • From the original game, few Black Flies can be seen from the menu screen before starting the game.
    • In Rebirth, however, never appear in the menu screen but few sprites still can be found in the game files.
Normal monsters
I Blob-button

I. Blob
More monsters coming soon...
Flies Black FlyAttack FlyMoterEternal FlyPooterFat FlyBoom FlyRed Boom FlyDrowned Boom FlySuckerSpitDart FlySwarm FlyRing FlyLevel 2 FlyFull FlyHush FlyBall of Flies
Spiders SpiderBig SpiderTriteRaglingRag TriteLevel 2 SpiderTicking SpiderBaby Long LegsCrazy Long LegsWall CreepBlind CreepRage Creep
Spheres BoilGutSackBlue BoilWalking Variants
Mulligans MulliganMulligoonMulliboomHiveSwarmerNestDrowned Hive
Headless HopperFlaming HopperLeaperPacerGusherSplasher
Gapers GaperFrowning GaperGurgleMr. MawFlaming GaperCyclopiaSkinnyRottyNullGreed GaperBlue GaperSwinger
Heads HorfPsychic HorfMawRed MawPsychic Maw
Globins GlobinGazing GlobinBlack GlobinDank Globin
Knights KnightSelfless KnightFloating KnightBone Knight
Blobs ClottyClotMega Clotty
Maggots MaggotChargerSpittyConjoined SpittyDrowned ChargerGrub
Body parts Mask + HeartBrainMemBrainGutsMama GutsEyeBloodshot EyeMom's HandDead Mom's HandScarred GutsNerve EndingStone Eye
Worms Para-BiteCod WormScarred Para-BiteRound WormNightcrawlerRoundyUlcer
Leeches LeechKamikaze LeechHoly Leech
Poop DipCorn DipBrown DipSquirtDank SquirtDinga
Skeletons BonyBlack BonyDeath's HeadDank Death's HeadFlesh Death's Head
Ghosts Lil' HauntWizoobRed Ghost
Bats One ToothFat Bat
Fatties FattyFlaming FattyConjoined FattyBlue Conjoined FattyPale Fatty
Hosts HostRed HostWalking HostWalking Red Host
Vises VisDouble VisChubberCage VisScarred Double Vis
Tumors TumorPsy TumorCamillo Jr.
Spikes Wall HuggerSlidePoky
Babies BabyAngelic BabyEmbryoImp
Homunculuses HomunculusBegotten
Keepers KeeperHanger
Grimaces Stone GrimaceVomit GrimaceGaping MawTurret GrimaceBrimstone Grimace
Oobs OobBlack Maw
Others FredLumpB. LickerDukieDopleEvil TwinMeatball

Start a Discussion Discussions about Black Fly

  • More than 3 orbitals?

    3 messages
    • It will have no effect whatsoever, unless the orbital you find is better than one of those you already have, in which case it will replace it.
    • you can gey up to 5 orbitals using the monster manual
  • Black fly gained quite a bit of weight fast...

    8 messages
    • It happened because if a normal, black fly hover around poop for a while, it might turn into a pooter, those flies that shoot blood shots. ...
    • I had a Fat fly(the two shot one) change into a pooter and I had no clue what happend.

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