For information on the character, see ???.
??? will appear lying down in the center of the room, crying on the floor. He shoots 12 high-velocity tears in a radial burst, some of them being purple and slightly homing, and will retaliate with streams of tears when hit. He will also spawn Flies continuously.
At 66% of his health, a light will shine on ???, and he jumps from the ground. He will then start shooting 4 large purple tears, which home slightly, in all directions. He will still retaliate with some tears when hit.
Triggered near 33% of ???'s health. ??? will grow angel wings, smile, and start floating. White beams will be randomly shot down from the sky (similar to Crack The Sky and White Pony), Angel Babies will start spawning frequently (up to a maximum of 6), and the same homing projectiles from before will be shot in six directions at the same time. At this point, ??? will no longer retaliate with tears when hit.
- Using The Bible during the or after the fight will instantly kill Isaac (similar to Isaac and Satan) unless he has The Wafer item.
- Like in the Isaac fight, using items with a high fire rate (such as Technology 2) is dangerous in this fight, as ??? will retaliate with a large amount of tears upon each hit. This also applies to effects which apply damage rapidly, such as Mom's Knife, Brimstone, or even the damage from orbitals like Distant Admiration.
- Applying slow effects such as Little Gish or Spider Bite to ??? will not affect the speed of his homing tears.
- Activating Mom's Bra will prevent ??? from counter-attacking when damaged for the duration of the effect.
- This boss is a reference to Ending 10, where Isaac finds ??? in the giant chest.
- ??? is technically an alternative version of Isaac (as a boss), having the same attacks only with some variants.
- ??? Is also a reference to BlueBaby, Edmund's Newgrounds name.
- The music for this fight is the same as the Isaac fight, My Innermost Apocalypse.
- In the second phase, ???'s tears are incorrectly shaped, while in the third phase, his tears are falling down correctly.
- Whenever he is curling up while in his third form, he might turn into Isaac for a single frame.
|Basement||Larry Jr. • Monstro • The Duke of Flies • Gemini • Steven • Famine|
|Cellar||Widow • Pin • The Duke of Flies • Famine • Gurdy Jr. • The Blighted Ovum|
|The Caves||Fistula • Peep • Gurdy • Chub • C.H.A.D. • Pestilence|
|Catacombs||The Husk • The Hollow • The Blighted Ovum • The Carrion Queen • Peep • Pestilence • The Wretched • Gurdy Jr.|
|The Depths||Loki • Monstro II • Gish • War • Mom|
|Necropolis||Mask of Infamy • Daddy Long Legs • The Carrion Queen • The Bloat • Loki • War • The Wretched • Mom|
|The Womb||Scolex • Blastocyst • The Bloat • Death • Conquest • Daddy Long Legs • Triachnid • Teratoma • Mom's Heart • It Lives|
|Utero||Teratoma • The Bloat • Death • Conquest • Daddy Long Legs • Triachnid • Lokii • Mom's Heart • It Lives|
|Sheol||The Fallen • Satan|
|First to fifth and seventh level||The Fallen • Headless Horseman|